基于结构方程模型的2型糖尿病气阴亏虚证实证研究  

Empirical Study on Qi-yin Deficiency Syndrome of Type 2 Diabetes Based on Structural Equation Model

作　　者：杨晓南[1] 刘宝忠[1] 闫丽辉[2] 王泓午[3] 赵铁牛[3] 

机构地区：[1]天津市红桥区中医医院,天津300132 [2]天津医科大学代谢病医院,天津300070 [3]天津中医药大学,天津300193

出　　处：《中国中医药信息杂志》2016年第4期28-31,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：天津市中医药管理局中医;中西医结合科研专项课题(13110)

摘　　要：目的验证2型糖尿病气阴亏虚证与病因和四诊信息的关系。方法收集天津市红桥区中医医院和天津医科大学代谢病医院门诊和住院的2型糖尿病患者资料,其中气阴亏虚证185例,其他证型351例。采用Logistic回归分析最大似然估计后退法筛选病因和四诊信息,在此基础上,采用结构方程模型最大似然估计法对2型糖尿病气阴亏虚证与病因和四诊信息的关系进行验证。结果模型的拟合优度指数(GFI)为0.909,均方根残差(RMR)为0.041,比较拟合指数(CFI)为0.942,表明拟合效果较好,并合理解释了气阴亏虚证与病因和四诊信息之间的关系。结论从单证候因素角度,利用结构方程模型验证了糖尿病气阴亏虚证与病因和四诊信息的关系。Objective To verify the relationship between qi-yin deficiency syndrome and the etiology and diagnostic information on type 2 diabetes mellitus.Methods Data of 185 cases of qi-yin deficiency syndrome of type 2 diabetes and 351 cases of other syndromes at TCM Hospital of Hongqiao District in Tianjin and Metabolic Disease Hospital of Tianjin Medical University were randomly collected. Etiology and diagnostic information of qi-yin deficiency syndrome were screened by the likelihood radio of forward step method by using Logistic regression analysis. On this basis, the relationship between qi-yin deficiency syndrome and the etiology and diagnostic information was verified by using maximum likelihood estimation method of the structural equation model.Results The goodness of fit index of the model (GFI) was 0.909; root mean square residual (RMR) of that was 0.071; comparative fit index (CFI) of that was 0.942, which suggested that the fitting effect of the model was good. The reasonable interpretation of the relationship between qi-yin deficiency syndrome and the etiology and diagnostic information was given. Conclusion From the aspect of single syndrome factors, the relationship between qi-yin deficiency syndrome and the etiology and diagnostic information on type 2 diabetes mellitus is verified.

关 键 词：结构方程模型 2型糖尿病 气阴亏虚证 LOGISTIC回归 症状 病因 

分 类 号：R259.871[医药卫生—中西医结合]