整合子在细菌生物膜耐药机制中的研究进展  

Research progress of integron in bacteria biofilm resistance mechanism

作　　者：唐夏[1,2] 王凌峰[2] 

机构地区：[1]内蒙古医科大学,包头014010 [2]内蒙古烧伤研究所内蒙古医科大学第三附属医院烧伤科,包头014010

出　　处：《中华临床医师杂志（电子版）》2016年第2期260-263,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：整合子在细菌生物膜耐药机制中有着重要作用。通过对整合子结构、功能及其参与细菌生物膜耐药方面的研究文献分析总结,发现整合子是细菌耐药机制的重要原因之一,在细菌生物膜耐药的发生、发展中起着重要作用。进一步研究细菌在生物膜状态和液相状态下整合子的表达情况,对阐明整合子在细菌生物膜中的耐药机制、探寻可能的治疗靶点具有重要意义。The integron palys an important role in bacteria biofilm resistance mechanism.Analyzing and summarizing the literatures of integron structure and function and the involvement in bacteria biofilm resistance mechanism find that integration is one of the important reasons of bacterial resistance mechanisms,there is an important role in the occurrence and development of bacteria biofilm drug resistance.Further study of the integron expression in biofilm state and liquid state of bacteria has important significance to elucidate the drug resistance mechanism of integron in bacteria biofilm and the possible therapeutic targets.

关 键 词：整合子类 细菌生物膜 耐药机制 

分 类 号：R446.5[医药卫生—诊断学]