三维斑点追踪成像技术定量评价心肌梗死患者左心功能的Meta分析  

Quantitative assessment of left ventricular function by three-dimensional speckle tracking imaging in myocardial infarction patients:Meta-analysis

作　　者：谭杰[1] 黄晶[1] 黄玉文[1] 姚沅清[1] 熊波[1] 朱叶锋[2] 

机构地区：[1]重庆医科大学附属第二医院心血管内科,重庆400010 [2]重庆医科大学附属第二医院超声科,重庆400010

出　　处：《中国介入影像与治疗学》2016年第3期177-182,共6页Chinese Journal of Interventional Imaging and Therapy

基　　金：国家自然科学基金面上项目(81370440)

摘　　要：目的采用Meta分析探讨三维斑点追踪成像(3D-STI)技术评价心肌梗死患者左心功能的价值。方法检索于2015年10月10日前公开发表的有关3D-STI评价心肌梗死患者左心功能的病例对照研究。以加权均数差(WMD)及95%可信区间(CI)作为合并统计量进行分析。结果最终纳入文献12篇,包含551例心肌梗死患者和431名健康对照者。Meta分析结果显示心肌梗死组患者左心室整体面积应变(GAS)、整体纵向应变(GLS)、整体径向应变(GRS)、整体环向应变(GCS)均显著低于对照组(GAS:WMD=8.58,95%CI 6.32~10.83,P<0.001;GLS:WMD=5.78,95%CI4.32~7.24,P<0.001;GRS:WMD=-15.93,95%CI-18.17^-13.68,P<0.001;GCS:WMD=6.13,95%CI 4.34~7.92,P<0.001)。结论 3D-STI可客观评价心肌梗死患者的左心功能。Objective To evaluate the value of three-dimensional speckle tracking imaging（3D-STI）for left ventricular function in myocardial infarction（MI）patients with Meta analysis.Methods Published case-control studies comparing the left ventricular function assessed by 3D-STI of MI patients and controls were searched before October 10,2015.Crude weighted mean differences（WMD）with 95% confidence intervals（CIs）were used to analysis.Results Twelve case-control studies were included with a total of 551 MI patients and 431 healthy control participants.Meta-analysis revealed that left ventricular global area,longitudinal,radial and circumferential strain were significantly impaired in the patients with MI compared to the controls（global area strain：WMD =8.58,95%CI 6.32—10.83,P〈0.001;global longitudinal strain：WMD=5.78,95%CI 4.32—7.24,P〈0.001;global radial strain：WMD=-15.93,95%CI-18.17—-13.68,P〈0.001;global circumferential strain：WMD =6.13,95%CI 4.34—7.92,P〈0.001）.Conclusion Left ventricular function in patients with MI can be objectively measured by 3D-STI.

关 键 词：三维斑点追踪 心肌梗死 应变 META分析 

分 类 号：R542.22[医药卫生—心血管疾病] R540.45[医药卫生—内科学]