聚桂醇泡沫硬化剂注射与腔内电凝治疗下肢静脉曲张的疗效对比  

Efficacy Comparison of Lauromacrogol Sclerotherapy and Intracavity Electrocoagulation in the Treatment of Varicose Vein of Lower Limb

作　　者：焦亚彬[1] 耿园园[2] 杨奋有[1] 王建军[1] 宇轲[1] 袁克芳 裴晓东[1] 曲杨[1] 

机构地区：[1]中国石油天然气集团公司中心医院心血管外科,河北省廊坊市065000 [2]中国石油天然气集团公司中心医院影像科,河北省廊坊市065000

出　　处：《中国全科医学》2016年第5期589-591,共3页Chinese General Practice

摘　　要：目的探讨泡沫硬化剂与腔内电凝治疗浅静脉曲张的疗效对比。方法选择中国石油天然气集团公司中心医院2012年8月—2013年7月收治的132例下肢静脉曲张患者(168条肢体),按照随机数字表法分为A和B两组,A组64例患者(84条肢体)行大隐静脉高位结扎剥脱+腔内电凝术,B组68例患者(84条肢体)行大隐静脉高位结扎剥脱+聚桂醇泡沫硬化剂栓塞治疗。对两组的手术时间、耗材费用、手术并发症、术后复发情况、溃疡好转情况等进行对比分析。结果两组患者均成功完成手术;A组每条患肢平均手术时间为(37.0±3.5)min,B组每条患肢平均手术时间为(34.0±4.6)min,两组间差异无统计学意义(t=0.476,P>0.05)。A组耗材平均费用为(19.5±0.6)元,B组耗材平均费用为(710.4±50.5)元,A组费用较B组明显降低,差异有统计学意义(t=3.845,P<0.01)。A组术后出现皮肤烧伤2例,血栓性静脉炎2例,隐神经损伤8例,B组出现血栓性静脉炎3例,隐神经损伤3例,两组并发症发生率间差异无统计学意义(χ2=1.556,P>0.05);术后随访1年,A组复发8例,B组复发1例,两组复发率间差异有统计学意义(χ2=4.226,P<0.05);A组患者溃疡愈合时间为(46.0±1.5)d,B组溃疡愈合时间为(18.0±2.0)d,两组间差异有统计学意义(t=2.342,P<0.05)。结论两种术式治疗下肢静脉曲张疗效均显著。聚桂醇泡沫硬化剂注射相对腔内电凝治疗费用略高,但对于治疗溃疡有一定优势,术后复发率相对较少。Objective To compare the efficacy of lauromacrogol sclerotherapy and intracavity electrocoagulation in the treatment of varicose vein of lower limb. Methods A total of 132 patients from China National Petroleum Corporation Central Hospital from August 2012 to July 2013,with varicose vein of lower limb（ 168 limbs） were enrolled and divided into group A and group B according to the random number table method,with 64 patients（ 84 limbs） in group A and 68 patients（ 84 limbs） in group B. Group A was administrated with high ligation and stripping of great saphenous vein ＋ intracavity electrocoagulation,and group B was administrated with high ligation and stripping of great saphenous vein ＋ lauromacrogol sclerotherapy. Analysis was made on duration of operation,expense on consumable items,complication of surgery,postoperative recurrence and ulcer recovery. Results Both groups finished surgery successfully. The average duration of surgery on a lesion limb was（ 37. 0 ± 3. 5）min for group A and（ 34. 0 ± 4. 6） min for group B,without significant difference between the two groups（ t = 0. 476,P 〈0. 015）. The average expense on consumable items was（ 19. 5 ± 0. 6） yuan for group A and（ 710. 4 ± 50. 5） yuan for group B,with group A lower than group B（ t = 3. 845,P 〈0. 01）. After surgery,2 cases of skin burn,2 cases of thrombophlebitis and 8cases of saphenous nerve injury occurred in group A; 3 cases of thrombophlebitis and 3 cases of saphenous nerve injury occurred in group B. The two groups had significant difference in the incidence of complications（ χ2= 1. 556,P 〉0. 015）. During the one- year follow- up after surgery,group A had 8 cases of recurrence and group B had one case of recurrence,there was significant difference between the two groups（ χ2= 4. 226,P 〈0. 015）. The healing time of ulcer was（ 46. 0 ± 1. 5） days for group A and（ 18. 0 ± 2. 0） days for group B,with significant difference between the two groups（ t = 2. 342, P 〈0. 015）.Conclusion T

关 键 词：静脉曲张 电凝术 聚桂醇泡沫硬化剂 疗效比较研究 

分 类 号：R543.6[医药卫生—心血管疾病]