静脉用脂肪乳剂与免疫调节  

Intravenous lipid emulsions and immuoregulation

作　　者：林海冠 

机构地区：[1]解放军第三O六医院普通外科,北京100101

出　　处：《中华临床营养杂志》2016年第1期58-62,共5页Chinese Journal of Clinical Nutrition

基　　金：306医院医药卫生科研青年基金项目（14QN10）

摘　　要：脂肪乳乳剂作为肠外营养支持的重要组成部分，提供能量和脂肪酸。因∞一6多不饱和脂肪酸的促炎作用，引发人们对脂肪乳剂影响免疫功能的担忧，但并无大量研究证实其不良免疫特性，目前各种新型脂肪乳通过改变脂肪乳剂中多不饱和酸、单不饱和酸、饱和脂肪酸含量及来源，期望减少“）一6多不饱和脂肪酸的用量。本文就目前常用脂肪乳剂与相关免疫调节作一综述。Lipid emulsion, as an important part of parenteral nutrition support, provides energy and fatty acids. The pro-inflammatory effect of ω-6 polyunsaturated fatty acids has triggered concerns of the possible influence of lipid emulsion on immune function, but few studies prove such adverse immune characteristics. At present new types of lipid emulsion are available by changing the concentration and sources of polyunsaturated acids, mono-unsaturated acid, and saturated fatty acids, attempting to reduce the amount of ω-6 polyunsaturated fatty acids. This paper reviewed the commonly used lipid emulsions at pres- ent and related immunoregulation.

关 键 词：肠外营养 脂肪乳剂 免疫 脂肪酸 

分 类 号：R459.3[医药卫生—治疗学]