广州花都地区泌尿系结石成分分析及危险因素研究  

Analysis and Risk Factors of Urinary Calculi Component in Huadu District of Guangzhou

作　　者：程璐[1] 李红艳[1] 习明[1] 万跃平[1] 华伟[1] 杨桂莲[1] 

机构地区：[1]南方医科大学附属广州市花都区人民医院,广东广州510800

出　　处：《中国医学创新》2016年第8期83-86,共4页Medical Innovation of China

基　　金：广州市花都区科技计划项目(HD14RX002;14-HDWS-009);广州市医学重点学科建设项目2013-2015(XM203190)

摘　　要：目的:探索广州市北部区域尿路结石成分特点,以及尿路结石发病主要危险因素,为尿石症患者的诊治以及预防提供科学依据。方法:选取2006年3月-2014年12月本院尿石症患者的结石标本330例,采用红外线光谱结石分析法进行结石成分鉴定;同时,将其中130例住院结石患者为病例组,140例同期在本院泌尿外科住院非尿石症者为对照组。采用非条件Logistic回归对42个研究变量进行分析。结果:330例结石样本中,270例(81.8%)为含钙结石,其中265例(80.3%)为含草酸钙结石,仅60例(18.2%)为混合结石。单因素非条件Logistic回归分析发现有16个因子有统计学意义(P<0.05);多因素Logistic逐步回归分析最终筛选出7个有关的因子,这些因素分别是喜欢口味重的咸食、经常参加健身运动、精神紧张度高、饮用生水、日饮水量少、家庭食用油动物油脂类型、植物油脂类型。结论:广州北部区域泌尿系结石主要以含钙结石为主;尿石症发病主要受饮食习惯和营养因素影响,其中个人因素的作用也不容忽视。Objective： To investigate the composition of urinary tract stones in northern Guangzhou and the main risk factors of urinary tract stones. To provide a scientific basis for the diagnosis of urolithiasis prevalence, prevention and treatment of urolithiasis. Method： 330 Calculi specimens of urolithiasis patients were selected in our hospital from March 2006 to December 2014, were to take the stones components were identified by infrared spectrum analysis.At the same time, 130 cases of hospitalized urolithiasis were set as case group, 140 cases of non urolithiasis the same period in our hospital were set as control group. 42 research variables using non conditional Logistic regression were analyzed. Result： 330 stone samples, 270 cases of calcium stones, accounting for 81.8%, which 265 patients （ 80.3% ） with calcium oxalate stones, only 60 cases of mixed stones, accounting for 18.2%. Single factor non conditional Logistic regression analysis found that 16 factors were statistically significant（ P〈0.05 ）. With multiple Logistic stepwise regression analysis ultimately selected 7 related factors, these factors were like heavy taste salty food, often take part in physical exercise, mental tension high, drinking unboiled water, less water, family cooking oil and animal oil types, vegetable types. Conclusion： Guangzhou northern region of urinary calculi mainly to calcium stones, urolithiasis is mainly affected by the dietary habits and nutritional factors, which personal factors also not allow to ignore.

关 键 词：尿石症危险因素 结石成分分析 

分 类 号：R691.4[医药卫生—泌尿科学]