辽宁省一般人群血和尿中钴、钼水平研究  

Cobalt and molybdenum levels in blood and urine among general population in Liaoning Province

作　　者：魏明至 王凯[1] 郑晓梅[1] 张瑶瑶[1] 庞妍[1] 何杨[1] 潘亚娟[2] 郑玉新[2] 闫慧芳[2] 田昊渊[2] 张蕴丽[3] 张云江 彭珊茁[1] 

机构地区：[1]沈阳市劳动卫生职业病研究所,辽宁沈阳110024 [2]中国疾病预防控制中心职业卫生与中毒控制所,北京100050 [3]辽宁医学院,辽宁锦州114000 [4]丹东市卫生监督所,辽宁丹东118002

出　　处：《中国工业医学杂志》2016年第1期19-23,共5页Chinese Journal of Industrial Medicine

基　　金：卫生部行业科研专项(200802020);国家科技支撑计划(2006BAI06B02);沈阳市科学计划项目(1091165-9-00)

摘　　要：目的调查辽宁省一般人群血和尿中钴、钼水平,分析其分布特点。方法采用多阶段分层整群随机抽样的方法,于2009—2010年在辽宁省东、中、西部三个地区抽取2105名对象进行问卷调查,并采集血液和尿液样品。采用电感耦合等离子体质谱法对血样和尿样进行钴、钼含量的检测,通过统计分析研究一般人群血液中钴、钼的分布水平。结果辽宁省一般人群血中钴、钼几何均数为0.153μg/L和0.38μg/L,尿中为0.516μg/L和23.88μg/L;在不同年龄和区域特征中差异均有统计学意义。结论辽宁省一般人群血和尿中钴、钼水平在不同年龄和区域特征中均存在差异。Objective To understand the cobalt and molybdenum levels in blood and urine among general population in Liaoning Province and their distribution features. Methods 2105 persons from 3 cities located at the eastern,central and western regions of Liaoning Province were recruited as study subjects by cluster random sampling method from 2009 to 2010. The general information was collected by questionnaire investigation,their blood and urine samples were also collected. The cobalt and molybdenum levels in blood and urine were detected by inductive coupled plasma mass spectrometry（ ICP-MS）,and their distribution characteristics were also analyzed by statistics method. Results It was showed that the blood geometric means（ GMs） of cobalt and molybdenum among the general population of Liaoning Province was 0. 153 μg / L and 0. 38 μg / L,respectively,and the urine GMs of cobalt and molybdenum was 0. 516 μg / L and 23. 88 μg / L,respectively. Conclusion The results suggested that there were some differences existed among in blood and urine levels of cobalt and molybdenum among the populations with different ages or from different regions in Liaoning Province.

关 键 词：钴 钼 血液 尿液 电感耦合等离子体质谱 

分 类 号：R446.1[医药卫生—诊断学] O614.812[医药卫生—临床医学]