针刀联合依那西普改善强直性脊柱炎脊柱功能障碍疗效观察  

Observation on Clinical Effects of Needle-knife Combined with Etanercept in Improving Spinal Dysfunction of Ankylosing Spondylitis

作　　者：王智明[1] 李伟青[1] 田雪梅[1] 陈文玉[1] 王娟娟[1] 

机构地区：[1]甘肃省中医院风湿骨病科,甘肃兰州730050

出　　处：《西部中医药》2016年第1期119-122,共4页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察针刀联合依那西普治疗强直性脊柱炎脊柱功能障碍的疗效。方法:将强直性脊柱炎患者60例随机分为2组各30例,治疗组接受针刀联合依那西普治疗,对照组只接受依那西普治疗,观察2组患者0、4、8、12周Bath强直性脊柱炎计量学指数(BASMI)、枕墙距、指地距、颌柄距、胸廓活动度、Schober试验、脊柱活动度的变化情况。结果:治疗12周后,2组患者胸廓活动度、Schober试验、脊柱活动度,BASMI、枕墙距、指地距、颌柄距减少,与治疗前比较差异有统计学意义(P<0.05);2组患者治疗后BASMI、胸廓活动度、Schober试验、脊柱活动度、枕墙距、指地距、颌柄距比较差异有统计学意义(P<0.05)。治疗组有效率为96.67%,对照组为86.67%,治疗组优于对照组,差异有统计学意义(P<0.05)。结论:针刀联合依那西普能有效改善强直性脊柱炎患者脊柱功能障碍。Objective： To observe clinical effects of needle-knife combined with etanercept in treating spinal dysfunction of ankylosing spondylitis. Methods： Sixty patients were randomized into two groups, 30 cases each group, the treatment group were treated with needle-knife combined with etanercept, the control group etanercept,Bath ankylosing spondylitis metrology index（BASMI）, occiput to wall distance, finger to floor distance, mandible to sternum distance, thoracic activity, schober test and spinal activity of the patients were observed in both groups at the zero, fourth, eighth and 12 th week. Results： In 12 weeks after treating, thoracic activity, schober test, spinal activity,BASMI, occiput to wall distance, finger to floor distance and mandible to sternum distance decreased in both groups,the difference showed statistical meaning when these indexes were compared with before treating（P〈0.05）; the difference had statistical meaning in the comparisons of BASMI, thoracic activity, schober test, spinal activity,occiput to wall distance, finger to floor distance, mandible to sternum distance between both groups after treating（P〈0.05）. Total effective rate of the treatment group was 96.67%, superior to 86.67% of the control group, and the difference showed statistical meaning（P〈0.05）. Conclusion： Needle-knife combined with etanercept could improve spinal dysfunction of ankylosing spondylitis effectively.

关 键 词：强直性脊柱炎 脊柱病变 针刀疗法 依那西普 

分 类 号：R593[医药卫生—内科学]