慢性阻塞性肺疾病患者在无氧阈时的运动风险分析  

Exercise-related risk at anaerobic threshold in patients with chronic obstructive pulmonary disease

作　　者：徐秋芬[1] 袁玮[1] 赵旭娟[1] 李宾[1] 王浩彦[1] 

机构地区：[1]首都医科大学附属北京友谊医院呼吸内科,100050

出　　处：《中华结核和呼吸杂志》2016年第2期110-112,共3页Chinese Journal of Tuberculosis and Respiratory Diseases

摘　　要：目的 观察慢性阻塞性肺疾病（慢阻肺）患者在无氧阈时的运动风险.方法 选择2013年2月至2014年6月首都医科大学附属北京友谊医院确诊的慢阻肺稳定期患者62例,其中男56例,女6例,平均年龄（66±8）岁.使用功率自行车进行逐渐递增和症状自限性心肺运动试验,采用V-slope和通气当量的方法确定无氧阈,分析在无氧阈强度下的症状、心电图、经皮氧饱和度和呼吸储备.结果 53例（53/62,85％）患者可确定无氧阈,无氧阈占最大摄氧量的（68±10）％.受试者在无氧阈状态下,经皮氧饱和度在安全范同内（94±2）％,呼吸储备较高（平均48％）,心电图未叶现心肌缺血改变,偶有房或室性期前收缩.结论 静息无明显缺氧的中蘑度慢阻肺患者可耐受较高强度的运动.Objective To investigate the exercise-related risk at anaerobic threshold （AT） in patients with chronic obstructive pulmonary disease （COPD）.Methods Sixty two patients [men 56,women 6,aged （66 ± 8） yr] with stable COPD in Beijing Friendship Hospital during 2013-2014,participated in this study.Incremental symptom-limited cardiopulmonary exercise test was performed on cycle ergometer.The AT was determined using the V-Slope technique and ventilatory equivalents for carbon dioxide and oxygen.Symptoms,10-lead electrocardiogram,oxygen saturation by pulse oximetry（SpO2） were monitored during exercise.Results The AT,detectable in 53 patients,occurred at （68 ± 10）% of peak oxygen uptake（peak VO2）.The SpO2 was in the safe range （94 ± 2） % and the respiratory reserve was relatively high at AT （i.e.48%）.Conclusions High-intensity exercise training can be performed in patients with moderate-to-severe COPD without resting oxygen desaturation.

关 键 词：肺疾病 慢性阻塞性 无氧阈 运动风险 

分 类 号：R563.9[医药卫生—呼吸系统]