肺炎支原体肺炎患儿急性期和恢复期血浆H-ficolin和L-ficolin水平分析  

Serum H-ficolin and L-ficolin levels in children with Mycoplasma pneumoniae pneumonia

作　　者：南子晴 华春珍[1,2] 王晓芳[1] 庞福珍 

机构地区：[1]杭州师范大学附属医院儿科,310015 [2]浙江大学医学院附属儿童医院 [3]天台县人民医院儿科

出　　处：《浙江医学》2016年第2期120-122,共3页Zhejiang Medical Journal

基　　金：浙江省医药卫生科技计划项目(2011KYA128);杭州市医药卫生科技计划项目(2011A020)

摘　　要：目的了解肺炎支原体肺炎患儿急性期和恢复期血浆中H-ficolin、L-ficolin水平的变化。方法采用ELISA法检测85例肺炎支原体肺炎患儿急性期和恢复期血浆H-ficolin、L-ficolin水平，并进行相关性分析。结果急性期H-ficolin水平18～252uq／ml，平均（119±59）ug／ml，恢复期H-ficolin水平0．3～26．5ug／ml，平均（10．1±57）ug／ml，急性期明显高于恢复期（Z=2．161．P=0.031）。急性期L-ticolin水平0．2～106μg／ml，平均（4．5±2.3）ug／ml，恢复期L-ficolin水平0．03～102μg／ml，平均（4．6±22）uq／ml，急性期和恢复期无统计学差异（t=0.245，P=0.807）。患儿急性期血浆H-ficoNn水平与L-ficolin水平明显相关（r=0.22，P=0.039）。结论H-ficolin可能参与儿童肺炎支原体肺炎疾病过程。Objective To determine serum H-ficolin and L-ficolin levels in children with Mycoplasma pneumoniae pneumonia （MPP）. Methods The levels of serum H-ficolin and L-ficolin at acute and convalescent stages were determined by ELISA in 85 children with MPP. Results The mean H-ficolin level at the acute stage was （11.9 ± 5.9） μ g/ml （1.8-25.2 μp g/ml）, which was significant higher than that at the convalescent stage （10.1 ±5.7）μ g/ml （0.3-26.5 μg/ml, 7,=2.161, P=0.031）. The mean L-ficolin levels at the acute stage and convalescent stage was （4.5 ±2.3）μ g/ml （0.2-10.6μ g/ml） and （4.6 ±2.2）μg/ml （0.03±10.2 μ g/ml）, respectively （t=0.245, P=0.807）. In acute stage serum H-ficolin level was correlated with L-ficolin level （r=0.22, P=0.039）. Conclusion H-ficolin may be involved in the disease process in Mycoplasma pneumonia in children.

关 键 词：肺炎支原体 肺炎 儿童 H-ficolin L-FICOLIN 

分 类 号：R725.6[医药卫生—儿科]