心周脂肪与心血管危险因素相关性研究进展  

Research progress on correlation between pericardial adipose tissue and cardiovascular risk factors

作　　者：孔维敏[1] 杨圣楠 楼青青[2] 陈玉凤[3] 高昕[2] 支颢[2] 冯纪涛[2] 

机构地区：[1]南京中医药大学护理学院,江苏南京210000 [2]南京中医药大学附属中西医结合医院,江苏南京210028 [3]江苏省中医院内分泌科,江苏南京210029

出　　处：《中国热带医学》2016年第2期190-194,共5页China Tropical Medicine

摘　　要：肥胖是公认的心血管危险因素,表现为脂肪在组织或器官的周围含量的增加,如腹部内脏脂肪、心周脂肪、非酒精性脂肪肝、颈部脂肪、肾脏脂肪的体积增加;心周脂肪(Pericardial Adipose Tissue,PAT)是异位脂肪的一种,虽然占全身脂肪组织比例较小,但是靠近冠状动脉,由冠状动脉供血;有较强的分泌功能,分泌炎症因子和脂肪酸直接进入冠状动脉,在冠状动脉硬化中起到比较重要的作用。就PAT与心血管危险因素做一综述。Obesity is recognized as a cardiovascular risk factor, characterized by fat accumulation in specificsurrounding tissues or organs of the body,such as increased abdominal visceral fat, pericardial adipose tissue, non alcoholicfatty liver disease, fat in the neck,fat around kidney. Pericardial Adipose tissue（PAT）is one of the ectopic fat, although lesspercentage of body fat, its location is close to the coronary artery and vascular supply is from the coronary arteries;it has strongsecretion and could secrete inflammatory factor and fatty acids directly into coronary artery, it may play a more important rolein the development of coronary atherosclerosis.In this paper, links between pericardial adipose tissue and cardiovascular riskfactors are reviewed.

关 键 词：心周脂肪 胰岛素抵抗 颈动脉中膜厚度 心血管危险因素 

分 类 号：R451[医药卫生—治疗学]