实时三平面斑点追踪技术评价肥厚型心肌病左心室整体及节段收缩期纵向应变的研究  

Assessment of left ventricular global and regional longitudinal strain in patients with hypertrophic cardiomyopathy by real-time tri-plane speckle tracking imaging

作　　者：江添[1] 刘明辉[1] 

机构地区：[1]中南大学湘雅二医院,长沙410011

出　　处：《新医学》2016年第2期113-116,共4页Journal of New Medicine

摘　　要：目的应用实时三平面斑点追踪显像(RT Tri-plane STI)技术评价肥厚型心肌病(HCM)患者左心室整体及节段收缩期纵向应变,探讨其在评估HCM患者左心室功能的临床应用价值。方法收集28例无左心室流出道梗阻、无明显临床症状、尚未接受临床干预性治疗的室间隔中上部HCM患者(HCM组)和30名健康人(对照组),行RT Tri-plane STI,获得左心室实时三平面二维动态图像并存储,将数据导入Echopac高级心血管分析系统进行相关处理,得到左心室整体及18节段收缩期纵向应变,并比较这些参数在2组间的差异,同时对比2组间的常规心功能检测值。结果2组间LVEF比较差异无统计学意义(P>0.05);HCM患者左心室基底段、中间段各室壁、部分心尖段及整体收缩期纵向峰值应变均低于对照组(P均<0.05)。结论 RT Tri-plane STI技术能无创、准确地评价HCM患者的整体及局部心肌功能,为临床早期诊治提供有价值的信息。Objective To assess the left ventricular（ LV） global and regional systolic longitudinal strain by real-time tri-plane speckle tracking imaging（ RT Tri-plane STI） and explore the clinical value of RT Tri-plane STI in evaluating LV function in patients with hypertrophic cardiomyopathy（ HCM）. Methods Twenty eight asymptomatic HCM patients with upper interventricular septal hypertrophy who had neither left ventricular outflow obstruction nor underwent interventional therapy were assigned into the HCM group and thirty healthy subjects were recruited in the control group. LV real-time tri-plane images were acquired and restored after RT Tri-plane STI. Digital echocardiographic data were transferred into Echopac multi-parameter analysis system. LV global and 18 segments systolic longitudinal strains were obtained. These parameters and conventional cardiac function data were statistically compared between two groups. Results Left ventricular ejection fraction did not significantly differ between the HCM and control groups（ P〉0. 05）. Compared with the control group,the longitudinal strain values of basal and middle segments,partial apical segment and global longitudinal peak strain were significantly decreased in the HCM group（ all P〈0. 05）. Conclusion RT Triplane STI is a noninvasive and effective approach of evaluating global and regional myocardial function in HCM patients,which provides valuable data for early diagnosis and treatment.

关 键 词：实时三平面 斑点追踪显像 肥厚型心肌病 左心室 纵向应变 

分 类 号：R542.2[医药卫生—心血管疾病]