合并不同并发症的老年高血压患者的衰弱检出率  

Prevalence of frailty in elderly hypertensive patients with different complications

作　　者：范利[1] 李建华[1] 胡亦新[2] 王蓉[3] 赵婷[3] 库洪安[4] 杨雪[5] 李银艺 张曼秀[4] 刘云霞[2] 马晓娜[2] 韩晓琪[2] 邹晓[1] 孙静[6] 李艳芳[7] 华琦[8] 

机构地区：[1]解放军总医院南楼心内科,北京100853 [2]解放军总医院保健科,北京100853 [3]解放军总医院综合外科,北京100853 [4]解放军总医院护理部 [5]解放军总医院南楼门诊部 [6]解放军总医院健康管理研究院 [7]北京安贞医院急诊科 [8]北京宣武医院心内科

出　　处：《中华高血压杂志》2015年第12期1151-1155,共5页Chinese Journal of Hypertension

基　　金：总后保健专项科研课题(12BJZ40)

摘　　要：目的比较不同年龄段及合并不同并发症的老年高血压患者衰弱的检出率。方法纳入2013-2015年在解放军总医院门诊查体的≥65岁老年高血压患者320例。采用调查问卷的形式对患者的一般情况、主要并发症等进行调查,并完成步速的评估。步速〈0.8m/s作为诊断衰弱的指标。结果老年高血压患者320例中,衰弱检出率为23.1%,其中65~〈80岁老年衰弱检出率为7.0%,≥80岁高龄老年衰弱检出率为32.0%,差异有统计学意义（P〈0.05）;高血压合并冠心病、肾功能不全、脑血管病衰弱检出率高于未合并者（均P〈0.05）;存在0~1种主要并发症的患者衰弱检出率为14.4%,2~3种者为23.4%,4~5种者为42.2%,检出率随并发症的增加而增加;存在4~5种并发症者衰弱的检出率高于0~1和2~3种者（均P〈0.05）。多因素Logistic回归分析发现,年龄（OR5.08,95%CI2.02~12.72,P〈0.05）、脑血管病（OR2.92,95%CI 1.30~6.62,P〈0.05）和肾功能不全（OR2.55,95%CI1.10~5.91,P〈0.05）与老年高血压患者衰弱相关。结论老年高血压患者衰弱的检出率随年龄及并发症的增加而增加,高龄、肾功能不全、脑血管病可能为高血压患者发生衰弱的危险因素。Objective To investigate the prevalence of frailty in elderly hypertensive patients with different complications.Methods A total of 320 elderly hypertensive patients aged 65 and over who underwent routine physical examinations in PLA general hospital from 2013 to 2015were enrolled. The information on demographic characteristics and hypertension complications were collected. All patients received gait speed measurement. A gait speed less than 0.8m/s was used as an indicator for frailty. Results The average prevalence rate of frailty was 23.1%,with 7.0% and 32.0%in patients of 65-80and≥80years respectively（P0.05）. The prevalence of frailty in hypertensive patients with coronary heart disease,renal insufficiency and cerebrovascular disease was significantly higher than those without（P0.05）.The prevalence rates in patients with 0-1,2-3and 4-5major complications were 14.4%,23.4% and 42.2% respectively,and the prevalence rate in patients with 4-5major complications was significantly higher（P0.05）than in other two groups. Multivariate logistic regression analysis indicated that elderly（OR5.08,95% CI 2.02-12.72,P0.05）,cerebrovascular disease（OR2.92,95% CI 1.30-6.62,P0.05）and renal insufficiency（OR2.55,95% CI 1.10-5.91,P0.05）were significantly associated with frailty.Conclusion The prevalence of frailty was increased with age and the number of complication in elderly hypertensive patients. The elderly,renal insufficiency and cerebrovascular disease may be risk factors for frailty.

关 键 词：老年 高血压 衰弱 并发症 

分 类 号：R544.1[医药卫生—心血管疾病]