基于三维彩色血管能量成像的子宫肌瘤射频消融的临床研究  

Clinical Study of Radiofrequency Ablation for Uterine Fibroids based on Three-dimensional Color Power Angiography

作　　者：赫飞飞 董晓秋[1] 邵小慧[1] 张立维[1] 戚云峰[1] 

机构地区：[1]哈尔滨医科大学附属第四医院超声科,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2015年第36期7058-7062,共5页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81271646)

摘　　要：目的:探讨三维彩色血管能量成像(three-dimensional color power angiography,3D-CPA)在射频消融(radiofrequency ablation,RFA)子宫肌瘤中的应用价值。方法:回顾性分析于我院行RFA治疗的48例子宫肌瘤患者,比较3D-CPA、CDFI(color Doppler flow imaging)两种方法指导下肌瘤血流分级、血管形态显示、初次消融时间、消融针数、完全消融率。根据超声造影(contrast-enhanced ultrasound,CEUS)结果对两组瘤体中消融不全的部分补充消融,记录两组的消融时间、消融针数并比较整个治疗过程的消融时间、消融针数。结果:3D-CPA、CDFI在显示血流分级、血管形态上差异有统计学意义(P<0.05)。初次治疗后,3D-CPA组92.3%(21/24)瘤体无造影剂灌注,CDFI组有68.2%(15/22)瘤体无造影剂灌注。二者比较差异有统计学意义(P<0.05)。整体消融过程中两组瘤体均达到完全消融时,3D-CPA组消融时间为(22.42±0.68)min,消融针数为(5.04±0.27)针,而CDFI组消融时间为(27.0±2.34)min,消融针数为(6.09±0.46)针,两组间差异均有统计学意义(P<0.05)。结论:基于3D-CPA可以显示子宫肌瘤内外血管数目、形态用以指导射频消融治疗子宫肌瘤的价值优于CDFI指导射频消融术。Objective： To investigate the application value of three-dimensional color power angiography（3D-CPA） in the treatment of radiofrequency ablation（RFA） for uterine fibroids. Methods： Retrospective analysis of 48 patients with uterine fibroids treated by RFA under guiding by 3D-CPA and color Doppler flow imaging（CDFI）. The differences of blood flow classification and blood vessel morphology, and the differences of initial ablation time, the ablation needle number and the complete ablation rates between the two groups were compared. The incompletely ablated uterine fibroids in the two groups were conducted supplementary ablation according to the results of CEUS. Then recorded the ablation time and the needle number. After that compared the difference of the ablation time and the number of the ablation of the whole treatment process. Results： There were differences between 3D-CPA and CDFI in showing blood flow classification and blood vessel morphology. And the differences were statistically signicant（P〈0.05）. After the initial treatment, 92.3%（21/24）of uterine fibroids in 3D-CPA group had no contrast infusion, while 68.2%（15/22）of uterine fibroids in CDFI group had no contrast infusion. There was statistically difference between the two groups（P〈0.05）. In the whole ablation process the ablation time of the 3D-CPA group was（22.42±0.68）min, the needle number was（5.04±0.27）, while the ablation time of the CDFI group was（27.0±2.34）min, the needle number was（6.09±0.46）. There was statistically difference between the two groups（P〈0.05）. Conclusions： 3D-CPA was superior to CDFI in displaying the number of internal and external vessels of uterine fibroids, the vascular morphology and the guidance of RFA for uterine fibroids.

关 键 词：子宫肌瘤 射频消融 三维彩色血管能量成像 彩色多普勒血流显像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R711.74[医药卫生—诊断学]