Synthesis of quinazolinones from o-aminobenzamides and benzyl amines under metal-free conditions  

作　　者：Xin-Xin Qi Zhen-Zhen Song Jin-Long Gong Zheng-Yu Fang Xiao-Feng Wu 

机构地区：[1]Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018, China [2]Department of Anal-colorectal Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China [3]Leibniz-Institut für Katalyse e.V. an der Universit t Rostock, 18059 Rostock, Germany

出　　处：《Chinese Chemical Letters》2016年第1期21-24,共4页中国化学快报（英文版）

基　　金：the financial supports from NSFC (No. 21472174);Education Department of Zhejiang Province (No. Y201432060);Zhejiang Sci-Tech University (Nos. 1206838-Y and 14062015-Y)

摘　　要：A convenient and transition-metal free protocol for quinazolinones synthesis with o-aminobenzamides and benzyl amines as substrates has been developed. Using H;O;as the oxidant, various quinazolinones were obtained in moderate to good yields under metal- and additive-free conditions.A convenient and transition-metal free protocol for quinazolinones synthesis with o-aminobenzamides and benzyl amines as substrates has been developed. Using H_2O_2 as the oxidant, various quinazolinones were obtained in moderate to good yields under metal- and additive-free conditions.

关 键 词：QUINAZOLINONES METAL-FREE Benzyl amine H2O2 

分 类 号：O626[理学—有机化学]