Rapid and mild synthesis of quinazolinones and chromeno[d]pyrimidinones using nanocrystalline copper(Ⅰ)iodide under solvent-free conditions  

作　　者：Shahrzad Abdolmohammadi Samira Karimpour 

机构地区：[1]Department of Chemistry, Faculty of Science, East Tehran Branch, Islamic Azad University

出　　处：《Chinese Chemical Letters》2016年第1期114-118,共5页中国化学快报（英文版）

基　　金：the financial support from the Research Council of East Tehran Branch, Islamic Azad University

摘　　要：This paper describes a very simple, efficient synthesis of quinazolinones and chromeno[d]pyrimidinones from the reaction of aryl aldehydes, urea/thiourea and active methylene compounds（dimedone/4-hydroxycoumarin） using nano-sized CuI particles under solvent-free conditions. The highlights of this new method are based on using an effective and recyclable catalyst, affording high yields of products,mild reaction conditions, facile work-up and purification.This paper describes a very simple, efficient synthesis of quinazolinones and chromeno[d]pyrimidinones from the reaction of aryl aldehydes, urea/thiourea and active methylene compounds（dimedone/4-hydroxycoumarin） using nano-sized CuI particles under solvent-free conditions. The highlights of this new method are based on using an effective and recyclable catalyst, affording high yields of products,mild reaction conditions, facile work-up and purification.

关 键 词：Chromeno[d]pyrimidinones Copper（Ⅰ） iodide nanoparticles QUINAZOLINONES Solvent-free conditions 

分 类 号：O626[理学—有机化学]