他达那非治疗慢性前列腺炎合并勃起功能障碍的疗效分析  被引量:12

Curative effect of small doses of tadalafil in the treatment for the chronic prostatitis combined with erectile dysfunction

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作  者:胡利霞[1] 祝存海[2] 涂雪松[3] 陈玉环[1] 李枫[1] 

机构地区:[1]孝感市中心医院妇产科,湖北孝感432000 [2]孝感市中心医院泌尿外科,湖北孝感432000 [3]孝感市中心医院药学部,湖北孝感432000

出  处:《中国性科学》2016年第2期15-17,共3页Chinese Journal of Human Sexuality

摘  要:目的:探讨他达那非应用于慢性前列腺炎(CP)合并勃起功能障碍(ED)的治疗效果。方法:选取我院收治的110例CP合并ED患者,将其随机分为观察组以及对照组,每组55例,两组患者均给予ɑ1受体阻滞剂坦索罗辛、前列疏通以及抗生素治疗,在此基础上观察组患者加用他达那非10mg,隔天1次,两组患者均治疗4周,治疗前后比较两组患者的CPSI评分以及IIEF-5评分,并比较两组治疗效果。结果:治疗后两组患者的CPSI评分以及IIEF-5评分均较治疗前显著改善,且观察组改善更加明显,观察组的治疗有效率为92.73%(51/55),对照组为72.73%(40/55),组间比较有统计学意义(P<0.05);干预前,两组患者SDS和SAS量表评分无统计学差异(P>0.05);观察组干预后SDS和SAS量表评分低于对照组,差异有统计学意义(P<0.05)。结论:他达那非联合传统治疗方法应用于CP合并ED患者能够显著改善慢性前列腺炎临床症状,改善患者的勃起功能,提高自信,改善生活质量。Objectives: To study the curative effect of small doses of tadalafil in the treatment of chronic prostatitis combined with erectile dysfunction. Method: 110 patients with CP combined ED in our hospital were selected and randomly divided into observation group and control group,55 cases in each group. Two groups were given solo sheen ɑ 1 receptor blockers,dredge and antibiotic for treatment. On the basis of that,the observation group also received tadalafil,10 mg / time,every two days a time. Two groups were all treatment for 4 weeks. The CPSI ratings and IIEF5 ratings before and after treatment and the therapeutic effect in two groups were compared. Results:After treatment,CPSI and IIEF5 score in two groups all significantly improved and more significant in the observation group. Treatment effective rate in observation group was 92. 73%( 51 /55),and 72. 73%( 40 /55) in control group,with statistically significant difference( P〈0. 05). Before intervention,SDS NHSS rating scale had no statistical difference( P〉0. 05); after the intervention,SDS and SAS scale score of observation group were lower than these in control group,with statistically significant difference( P〈0. 05). Conclusion: Small dose of tadalafil combined traditional method applied in the treatment of CP combined ED patients can significantly improve the clinical symptoms of chronic prostatitis,improve the patient's erectile function,self- confidence and the quality of life.

关 键 词:他达那非 慢性前列腺炎 勃起功能障碍 

分 类 号:R697.3[医药卫生—泌尿科学] R698.1[医药卫生—外科学]

 

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