鬼臼毒素酊联合电灼治疗尖锐湿疣疗效及复发率研究  

Efficacy and relapse rate in genital warts patients treated with podophyllotoxin joint fulguration

作　　者：周敏 陈艳[2] 

机构地区：[1]慈溪市第三人民医院皮肤科,浙江宁波315324 [2]宁波市第二医院皮肤科,浙江宁波315010

出　　处：《中国性科学》2016年第2期68-70,共3页Chinese Journal of Human Sexuality

摘　　要：目的:研究鬼臼毒素酊联合电灼治疗尖锐湿疣疗效及复发率。方法:选择2013年1月至2014年12月我院及宁波市第二医院收治的120例尖锐湿疣患者。按照入院顺序将患者分为观察组(60例)和对照组(60例)。对所有患者采用电灼术法去除所有疣体,观察组患者在此基础上联合使用鬼臼毒素酊。比较两组患者治疗后的疗效;观察比较两组患者在治疗后的不良反应状况和复发情况。结果:治疗之后观察组患者总的有效率(93.33%)显著高于对照组(71.67%),P<0.05。两组患者的局部不良反应小,均没有出现系统性的不良反应,其不良反应没有明显的差异(P>0.05)。观察组患者在治疗后的复发率(23.33%)显著低于对照组(56.67%),P<0.05。结论:尖锐湿疣患者采取鬼臼毒素酊联合电灼治疗方法,其疗效较好,具有较低的复发率,值得广泛推广使用。Objectives： To study the therapy efficacy and relapse rate in genital warts patients treated with podophyllotoxin joint fulguration. Methods： 120 patients with genital warts in our hospital from January 2013 to December2014 were selected and divided into observation group（ 60 cases） and control group（ 60 cases） according to the order of admission. All patients were treated with fulguration to remove wart and the observation group received additional podophyllotoxin on such basis. The efficacy,adverse reactions and relapse of the two groups were compared after treatment.Results： After treatment,the total effective rate in the observation group（ 93. 33%） was significantly higher than the control group（ 71. 67%）,with statistically significant difference（ P〈0. 05）. There were few local adverse reactions and no systemic adverse reactions,with no significant difference between the two groups（ P〉0. 05）. The relapse rate in ob-servation group（ 23. 33%） after treatment was significantly lower than that of control group（ 56. 67%）,with statistically significant difference（ P〈0. 05）. Conclusion： The podophyllotoxin joint fulguration is of great efficacy and low relapse rate in the treatment of patients with genital warts,which is worthy widely application.

关 键 词：鬼臼毒素酊 电灼 尖锐湿疣 疗效 复发率 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]