益肾清利方治疗特发性弱精子症临床研究  

Clinical study of Yishen Qingli Decoction on treatment of idiopathic weak sperm sterility

作　　者：孙建明[1] 马燕凤[2] 夏伟[3] 薛慈民[4] 刘鹏[1] 韩文均[1] 

机构地区：[1]上海市第七人民医院男性病科,上海200137 [2]上海市第七人民医院康复一科,上海200137 [3]上海市第七人民医院科研科,上海200137 [4]上海中医药大学附属曙光医院中医外科,上海200021

出　　处：《中国性科学》2016年第2期93-95,共3页Chinese Journal of Human Sexuality

基　　金：上海市浦东新区中医药事业发展专项资金(院内制剂和经验方规范化临床验证)(PDYNZJ2014-20);上海市浦东新区名中医及名中医工作室建设项目(PDZYXK-3-2014011);上海市浦东新区传统型中医临床示范学科建设(中医不育症专科)(PDZYXK-2013001)

摘　　要：目的:探讨益肾清利法治疗特发性弱精子不育症疗效及作用机制。方法:将60例特发性弱精子不育症患者随机分为两组,治疗组30例采用益肾清利法治疗,对照组30例口服中成药五子衍宗丸治疗。治疗前后对患者进行综合疗效评价,观察有无妊娠、精液质量检查和血清性激素检测。结果:总有效率治疗组为86.67%;对照组为83.33%,两组比较,差异有显著性意义(P<0.05)。治疗组治疗前后组内比较,精子密度、精子成活率、快速前向运动(a级)、慢速或呆滞前向运动(b级)、睾酮(T)、卵泡刺激素(FSH)、黄体生成素(LH)差异有统计学意义(P<0.05)。结论:益肾清利法治疗特发性弱精子不育症达到预期疗效。Objectives： To explore the diagnosis and treatment mechanism of Yishen Qingli Decoction on treatment of idiopathic weak sperm sterility. Methods： 60 patients with idiopathic weak sperm sterility were randomly divided into 2 groups,each of 30 cases. Treatment group received Yishen Qingli Decoction for treatment,while control group orally took Chinese patent medicine abital yan zong pill for treatment. The synthetic evaluation of curative effect before and after treatment was conducted,and pregnancy,semen quality and the serum sex hormones（ T,HSH,LH） were tested. Results： The total effective rate in treatment group and control group was 86.67% and83. 33% respectively,with significant differences（ P〈0. 05）. Difference in the sperm density,sperm survival rate A,A＋ B,T,FSH and LH in the treatment group before and after treatment was statistically significant（ P〈0. 05）.Conclusion： Yishen Qingli Decoction has the desired effect in treatments for idiopathic weak sperm sterility.

关 键 词：益肾清利法 特发性弱精子不育症 临床研究 

分 类 号：R698.2[医药卫生—泌尿科学]