3D-ASL联合MRA诊断DWI阴性TIA  

Application of 3D-ASL and MRA in Patients with TIA with Negative Diffusion Weighted Imaging

作　　者：王树春[1] 辛毅[1] 马智军[1] 房伟[1] 

机构地区：[1]山东省潍坊市益都中心医院

出　　处：《中国医学计算机成像杂志》2016年第1期5-8,共4页Chinese Computed Medical Imaging

摘　　要：目的:探讨3D-ASL联合MRA在DWI阴性TIA患者中的临床应用价值。方法:回顾性分析临床确诊的DWI阴性TIA患者的3D-ASL及MRA资料共55例,正常对照组的3D-ASL及MRA资料共32例,分析病变的检出率、血管狭窄程度与r CBF比值的关系及两组的差别。结果:3D-ASL诊断TIA的敏感性为70.91%;在血管的轻度狭窄、分支稀少及中度狭窄中病例组与对照组有统计学差异(P<0.05),在重度狭窄组两者无统计学差异(P>0.05)。结论:3D-ASL与MRA联合应用既能显示脑组织灌注异常范围及程度,又能明确血管病变部位及狭窄程度,提高DWI阴性TIA诊断的特异性及敏感性,为临床精细、个体化的治疗方案提供重要依据。Purpose： To discuss the clinical application value of 3D-ASL and MRA in patients with TIA with negative diffusion weighted imaging（DWI）. Methods： 3D-ASL and MRA data of 55 cases of negative DWI TIA patients and 32 normal volunteers were retrospectively reviewed. The lesion detective rate, the relation between the degree of vascular stenosis and r CBF ratio, and the difference between two groups were analyzed. Results： The sensitivity of 3D-ASL in diagnosis of TIA was 70.91%; There were significant differences of r CBF ratio between the case group with mild and moderate vascular stenosis and control group（P〈0.05）. There was no significant difference between the case group with severe stenosis and control group（P〈0.05）. Conclusion： Range of perfusion abnormalities and damage degree of brain tissue can be displayed by 3D-ASL combined with MRA, and the diagnostic specificity and sensitivity of DWI negative TIA can also be improved with the combined application.

关 键 词：短暂性脑缺血发作 磁共振扩散加权成像 动脉自旋标记法 磁共振血管造影术 

分 类 号：R445.2[医药卫生—影像医学与核医学]