高龄男性原发性高血压患者高尿酸血症患病率调查及相关因素分析  

Incidence of hyperuricemia in elderly male primary hypertensive patients and its related factors

作　　者：刘灿[1] 黄雨晴[1] 余雪菊 冯颖青[1] 

机构地区：[1]广东省人民医院心内科(广东省医学科学院)广东省心血管病研究所,广州510080

出　　处：《中华老年心脑血管病杂志》2016年第3期251-253,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

基　　金：广东省自然科学基金(S2013010016575;2015A030313660);广州市科技计划(2014y2-00140;1563000381);广东省科技计划(2014B020212008)

摘　　要：目的，探讨高龄男性原发性高血压患者高尿酸血症的患病率及相关因素。方法从广东省人民医院管理的社区高血压数据库中选取资料完整的高龄男性原发性高血压患者200例，其中80～90岁原发性高血压患者185例，年龄〉90岁原发性高血压患者15例。抽取空腹血检测尿酸、血生化等指标，分析高龄男性原发性高血压患者高尿酸血症患病率及分布情况，同时用logistic回归进行高尿酸血症相关因素分析。结果高龄男性原发性高血压患者尿酸为（412．21±105．23）μmol／L，总患病率为49．5％。80～90岁与年龄〉90岁高龄男性原发性高血压患者高尿酸血症患病率比较，差异无统计学意义（49．7％72546．7％，P〉0．05）。logistic回归分析显示，TC、TG、体质量指数、腰臀比、腰围为高龄男性原发性高血压患者高尿酸血症的相关影响因素（P〈0．05，P〈0．01）。结论高龄男性原发性高血压患者高尿酸血症患病率高，且高尿酸血症相关因素多为代谢综合征相关因紊。Objective To study the incidence of hyperuricemia in elderly male prima＇ry hypertensive patients and its related factors. Methods Two hundred elderly primary hypertensive patients （185 aged 80-90 years with hypertension, 15 aged 〉90 years with hypertension） were included in this study. Fasting blood samples were taken to detect their uric acid （UA）and biochemical data. The incidence of hyperuricemia was analyzed. Hyperuricemia-related factors were andlyzed by logistic regression analysis. Results The serum UA level was 412.21± 105.23 gmol/L and the total incidence of hyperurieemia was 49.5% in the elderly male primary hypertensive patients. No significant difference was found in the incidence of hyperuricemia between the elderly male primary hy- pertensive patients aged 80-90 years and those aged 〉90 years （49. 7% vs 46.7%,P〉0.05）. Logistic regression analysis showed that serum TG andTC level, BMI, waist circumference and waist-hip ratio were the independent risk factors for hyperuricemia in elderly male primary hypertensive patients （P〈0.05,P〈0.01）. Conclusion The incidence of hyperuricemia is high in eld- erly male primary hypertensive patients and is related with metabolic sysndrome.

关 键 词：高血压 高尿酸血症 尿酸 患病率 代谢疾病 

分 类 号：R544.1[医药卫生—心血管疾病]