海水吸入型急性呼吸窘迫综合征发病机制的研究进展  

Study progress on mechanisms of seawater inhalation induced acute respiratory distress syndrome

作　　者：王瑞璇[1] 马李杰[1] 金发光[1] 

机构地区：[1]第四军医大学唐都医院呼吸内科,西安710038

出　　处：《国际呼吸杂志》2016年第1期60-64,共5页International Journal of Respiration

摘　　要：淹溺在全球意外伤害中排名第三，且是儿童意外死亡的第二大原因。海水吸入后，若未能合理救治可发展为海水吸入型急性呼吸窘迫综合征（seawater inhalation induced acute respiratory distress syndrome，SW—ARDS），病死率极高。大量研究表明，肺组织水肿、肺部炎症反应、肺组织细胞代谢紊乱、细胞凋亡及自噬等参与SW—ARDS的发生和发展，现将有关发病机制作一综述。Drowning is the third accidental death cause in the world, more importantly, it is also the second leading cause of accidental death for children. Seawater inhalation would result in seawater inhalation induced acute respiratory distress syndrome （SW-ARDS） with a high mortality if the condition was not treated reasonably. Continuous evidences have indicated that pulmonary edema, inflammation in lung, metabolic disorder of lung tissue cells, cell apoptosis and autophagy participate in the occurrence and development of SW-ARDS. The article reviews the mechanisms of SW-ARDS.

关 键 词：海水 急性呼吸窘迫综合征 发病机制 综述 

分 类 号：R563.8[医药卫生—呼吸系统]