高频振荡通气平均气道压选择的临床进展  

Clinical advances in selection of mean airway pressure of high-frequency oscillatory ventilation Clinical advances in selection of mean airway pressure of high-frequency oscillatory ventilation

作　　者：谈莉[1] 刘松桥[1] 杨毅[1] 

机构地区：[1]东南大学附属中大医院重症医学科,南京210009

出　　处：《国际呼吸杂志》2016年第1期65-68,共4页International Journal of Respiration

基　　金：国家自然科学基金项目（81372093、81170057、81370180）;江苏省卫生厅面上科研课题（H201432）

摘　　要：ARDS是临床常见呼吸衰竭类型，肺保护性通气策略是其重要临床进展。高频振荡通气理论上是肺保护性的机械通气方式，其机械通气参数的设置尤其是平均气道压的合理选择对其临床应用具有重要意义，但是目前临床上尚无统一的设定标准。临床研究及动物实验主要以专家共识、P—V曲线法、最大氧合法、CT法、电阻抗断层显像技术等选择平均气道压，但临床平均气道压合理的选择方法及其应用仍有待进一步探索。Acute respiratory distress syndrome is a devastating clinical syndrome and the lung- protective strategy is the key point of its therapy. Theoretically, high-frequency oscillatory ventilation （HFOV） is an optimal lung-protective strategy. The settings of HFOV, especially the proper selection of mean airway pressure （mPaw） are meaningful to its cli/iieal use, but so far there is no unified standard of the setting of mPaw. The methods involved in the clinical researches and animal experiments are based on expert consensus, pressure-volume curve, oxygenation, CT, electrical impedance tomography and so on. However, the methods used to select the proper mPaw still need to be further studied.

关 键 词：高频振荡通气 平均气道压 急性呼吸窘迫综合征 

分 类 号：R563.8[医药卫生—呼吸系统]