舒肝调冲汤治疗女性迟发性痤疮临床观察  

Clinic observation for Shugan Tiaochong Decoction to cure female delayed acne

作　　者：李丽琼[1] 黄云 

机构地区：[1]云南中医学院,昆明650000 [2]云南省文山州中医院,云南文山663000

出　　处：《中华中医药杂志》2016年第3期1126-1128,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：云南省教育厅立项项目(No.2012Y057)~~

摘　　要：目的:观察舒肝调冲汤治疗女性迟发性痤疮的临床疗效及对外周血中性激素水平的影响。方法:70例患者随机分成两组:治疗组给予舒肝调冲汤内服,对照组给予清热暗疮片内服,疗程28d,观察治疗前后两组的临床疗效、复发情况及不良反应。对所有患者治疗前后外周血中性激素水平进行检测。结果:治疗组总有效率为91.7%,对照组总有效率为73.5%,治疗组总有效率显著优于对照组(P<0.01);睾酮(T)水平差异具有统计学意义(t=5.391,P<0.05),雌激素(E2)水平比较差异具有统计学意义(t=3.591,P<0.05);其余性激素水平无统计学意义。结论:舒肝调冲汤治疗女性迟发性痤疮疗效优于清热暗疮片组,具有疗效稳定、复发率低、不良反应少等优势;并能降低女性迟发型痤疮患者体内的睾酮(T)水平,并升高雌二醇(E2)水平,过调节体内性激素水平而发挥治疗作用。Objective： To observe sex hormone levels and curative effect of female delayed acne. Methods： To divide randomly 70 cases into two groups; treatment group took Shugan Tiaochong Decoction; matched group took Qingre Anchong Tablets; the period of treatment was 28 days. Curative effect, reappearance, side effect were observed before and after treatment and dynamically all cases, sex hormone levels were tested. Results： the treatment group total effective rate was 91.7%; the matched group total effective rate was 73.5%; the curative effect of treatment group was adventage over matched group（P0.01）; testoterone（t=5.391, P0.05） and estradiol（t=3.591, P0.05） had statistical significance; other hormone had no statistical significane. Conclusion： The curative effect of Sugang Tiaochong Deonction has good efficacy, low recurrence rate, small side effect and could adjust normally sex hormone levels that might have curative effect to female delayed acne.

关 键 词：女性迟发性痤疮 舒肝调冲汤 中医疗法 临床研究 性激素水平 

分 类 号：R275.9[医药卫生—中西医结合]