我院2011～2015年严重药品不良反应分析  

Analysis of severe adverse reactions from 2011 to 2015

作　　者：龚世菊[1] 王芳[1] 谭文明[1] 

机构地区：[1]广东省江门市中心医院药学部,江门529700

出　　处：《北方药学》2016年第3期160-161,共2页Journal of North Pharmacy

摘　　要：目的：对2011~2015年我院上报的严重药品不良反应进行统计分析,为药品风险管理提供数据为临床安全用药提供参考。方法：收集广东省药品不良反应管理平台中我院2011~2015年上报严重药品不良反应,利用EXECL记录上报病例患者性别、年龄、药理作用分类、ADR分类、用法用量、合并药品系统损害及转归进行分析。结果：纳入分析的严重ADR的报告共计155例,男女比例无差异,严重不良反应以50岁以上、静脉给药、抗肿瘤药较多见,绝大多数严重药品不良反应结局治愈或好转。结论：加强药物不良反应上报监管及引导,注重中药注射剂质量提升和临床合理使用,可能有助于减少严重药品不良反应。Objective：To analyze severe adverse reactions（ADR）reports in hospital from 2011 to 2015 in order to provide data in drug risk management and their clinical safe use to supply reference. Methods：All ADR reports from the central hospital of Jiangmen during the years of 2011 to 2015 in the Guangdong Center for ADR Monitoring Database were collected and record ages, analyzed. EXECL were used to record the gender, age, pharmacological function classification, ADR classification, usage and dosage, combined drug system damage and prognosis. Results：155 cases were collected. There is no difference between male and female, serious adverse reactions occurred in the population over 50 years old, intravenous administration, using anti tumor drugs. The vast majority of serious adverse drug reaction cure or improve. Conclusion：To strengthen the supervision and guidance of adverse drug reactions, pay attention to the quality of traditional Chinese medicine injection and clinical rational use may help to reduce the occurrence of serious adverse reactions.

关 键 词：严重药品不良反应 药物 合理用药 

分 类 号：R969.3[医药卫生—药理学]