Narcotrend麻醉深度监测在全麻中的应用  

Application of Narcotrend Monitor to General Anesthesia

作　　者：邓佳[1] 蒋璐[1] 许婷[1] 蔡兵[1] 

机构地区：[1]四川省医学科学院.四川省人民医院麻醉科,四川成都610072

出　　处：《四川医学》2016年第2期167-170,共4页Sichuan Medical Journal

摘　　要：目的探讨Narcotrend麻醉深度监测仪用于丙泊酚-瑞芬太尼全凭静脉麻醉的优越性。方法 100例全麻下行后腹腔镜肾切除的患者,随机分为N组(Narcotrend监测组)、E组(经验给药组)。两组患者均采用丙泊酚-瑞芬太尼全凭静脉麻醉,N组术中调整丙泊酚和瑞芬太尼输注速度将NTS维持在D2-E0水平,E组由麻醉医生根据临床体征和经验调节输注速度。结果 N组丙泊酚和瑞芬太尼的平均输注速度小于E组;N组MAP、HR波动较E组更小;N组患者术中NTS处在D2-E0水平的比例明显高于E组;N组患者呼唤睁眼时间、拔管时间和定向力恢复时间少于E组;两组患者苏醒期VAS评分、不良反应发生率、术中知晓发生率差异均无统学意义(P>0.05)。结论 Narcotrend麻醉深度监测应用于全凭静脉麻醉中,能更精确的控制麻醉深度,减少丙泊酚和瑞芬太尼用量,减少患者生命体征的波动,缩短患者苏醒时间,但对术中知晓发生率无明显影响。Objective To investigate the superiority of Narcotrend monitor for propofol and remifentanil total intravenous anesthesia.Methods 100 cases of patients with laparoscopic nephrectomy under general anesthesia were divided into group N（ Narcotrend group） and group E（ experience delivery group） randomly.Patients in both two groups were treated with propofol and remifentanil total intravenous anesthesia.The infusion speed of propofol and remifentanil in group N was adjusted to maintain the NTS to level D2-E0 and it in group E was regulated by anesthetists according to clinical signs and experience.Results The average infusion speed of propofol and remifentanil of group N was slower than group E.The fluctuation of MAP and HR in group N was smaller.The ratio of level D2-E0 NTS in group N was apparently higher.The calling eye opening time,extubation time and recovery time of group N patients was shorter.There were no difference in patients＇ VAS score,adverse reactions rate,and intraoperative awareness rate between two groups.Conclusion The application of Narcotrend monitor to total intravenous anesthesia could control of the depth of anesthesia more precisely,reduce the dosage of propofol and remifentanil,reduce the fluctuations in patients＇ life signs and shorten the recovery time of patients,but it made no significant difference to the intraoperative awareness rate.

关 键 词：Narcotrend麻醉深度监测仪 全凭静脉麻醉 麻醉深度 

分 类 号：R614.2[医药卫生—麻醉学]