昆明市MSM人群中同性恋与双性恋者指长比分析  

The study on the digit ratio between homosexuality and bisexuality in Kunming MSM population

作　　者：李彩霞[1,2,3] 贾曼红[2] 马艳玲[2] 罗红兵[2] 李琪[1,2] 王玉淼 李真晖 丁文立[2] 宋丽军[2] 章任重[2] 郭敏[1,2] 韦焘[1,2] 李晓岚[3] 曹兰[3] 陆林[1,2] 

机构地区：[1]昆明医科大学公共卫生学院,云南昆明650500 [2]云南省疾病预防控制中心性病艾滋病防治所,云南昆明650031 [3]昆明医科大学附属延安医院皮肤科,云南昆明650051

出　　处：《中华疾病控制杂志》2016年第2期177-179,187,共4页Chinese Journal of Disease Control & Prevention

基　　金：国家科技重大专项(2013ZX10004-906);云南省科技厅-昆明医科大学应用基础研究联合专项(2016年);昆明市延安医院院内课题(2014-2017年)

摘　　要：目的探讨昆明市男同性恋与男双性恋男男性行为者（men having sex with men,MSM）人群指长比的特点,为制定针对性的干预措施提供科学依据。方法采用人类体质测量法,测量89例男同性恋、26例男双性恋和115例对照组双手第2~5指的长度,并分析其指长比（2D∶3D、2D∶4D、2D∶5D、3D∶4D、3D∶5D、4D∶5D）。结果昆明市MSM人群右手2D：4D和2D：5D高于对照组;昆明市MSM人群指长比的分布特点为：2D∶3D〈2D∶4D〈3D∶4D〈2D∶5D〈4D∶5D〈3D∶5D;在MSM人群中,同性恋与双性恋者之间右手2D∶4D和2D∶5D差异无统计学差异（t_1=0.205,P_1=0.838;t_2=0.700,P_2=0.486）。结论指长比（特别是右手的2D∶4D）可反映个体出生前雄激素暴露水平,其大小与母体孕期的睾酮呈正相关,与雌激素呈负相关,被认为是个体出生前受母体性激素影响的体质学标记。据此,推测胚胎期母体低水平的雄激素及高水平的雌激素暴露可能会影响个体出生后的性取向,但用指长比尚不能区别出同性恋者与双性恋者。Objective To explore the characteristics of digit ratio between homosexuality and bisexuality in Kunming msm polulation,in order to reduce discrimination and to provide scientific evidence for targeted intervention measures. Methods Physical measurements were used to study digit ratio（ 2D ∶ 3D,2D ∶ 4D,2D ∶ 5D,3D ∶ 4D,3D ∶ 5D,4D ∶ 5D） of hands in 89 homosexuality,26 bisexuality and 115 controls. Results The 2D ∶ 4D and 2D ∶ 5D of MSM was higher than control. The mean values of digit ratio of MSM presented a trend as 2D ∶ 3D,2D ∶ 4D,2D ∶ 5D,3D ∶ 4D,3D ∶ 5D,4D ∶ 5D. According to the 2D ∶ 4D and 2D ∶ 5D,there was no significant difference between homosexual men and bisexual men（ t1= 0. 205,P1= 0. 838; t2= 0. 700,P2= 0. 486）. Conclusions Digit ratio（ especially the 2D ∶ 4D of right hand） can reflect the individual prenatal testosterone level. The ratio was positively correlated with maternal pregnancy testosterone,and was negatively correlated with maternal pregnancy estrogen. So,the digit ratio is considered to be a prenatal individual biomarker which is affected by maternal pregnancy sex hormones. Low levels of testosterone and high levels of estrogen exposure during embryonic period could affect the individual＇s sexual orientation. However,using digit ratio cannot distinguish the homosexuals and bisexuals.

关 键 词：同性恋 男性 流行病学研究 对照组 

分 类 号：R181.1[医药卫生—流行病学] R512.9[医药卫生—公共卫生与预防医学]