不同参照物评价超声弹性成像在甲状腺肿瘤良恶性鉴别诊断中的意义及影响因素  

Significance and Influence Factors of Different Reference Objects in the Differential Diagnosis of Benign and Malignant Thyroid Tumor

作　　者：孙晓丹[1] 谢德金[1] 吴壮雄[1] 王家刚[1] 

机构地区：[1]汕头市中心医院,广东汕头515031

出　　处：《临床医学工程》2016年第3期268-269,共2页Clinical Medicine & Engineering

基　　金：2014年汕头市科技计划项目(汕府科[2014]62号-19)

摘　　要：目的探讨不同参照物评价超声弹性成像在甲状腺肿瘤良恶性鉴别诊断中的意义及影响因素。方法选择我院甲状腺肿瘤患者120例,先用常规超声进行检查获得相应的指标,再对病灶进行超声弹性成像,分别以正常甲状腺组织及胸锁乳突肌作为参照,采用5级弹性评分法及应变率比值法进行鉴别,以最终病理结果作为金标准,比较两种参照物的敏感度和特异度,对影响因素进行分析。结果共检查出甲状腺结节142个,参照正常甲状腺组织准确性、敏感性和特异性分别为80.99%、93.66%、76.06%;参照胸锁乳突肌组织准确性、敏感性和特异性分别为79.58%、91.55%、78.87%（P〉0.05）。参照正常甲状腺组织弹性评分0-2级121个,3-4级21个;参照胸锁乳突肌组织弹性评分0-2级119个,3-4级23个（P〉0.05）。两种参照物恶性结节弹性应变率均高于良性结节（P〈0.05）。结论正常甲状腺组织和胸锁乳突肌均可作为超声弹性成像鉴别甲状腺肿瘤良恶性的参照物。Objective To investigate the significance and influence factors of different reference objects in the differential diagnosis of benign and malignant thyroid tumors. Methods 120 cases of thyroid cancer were selected, and the corresponding indices were examined by conventional ultrasound. The lesions were performed by ultrasonic imaging. 5 grades and strain rate were used to differentiate the normal thyroid tissue and the strain rate. Results 142 thyroid nodules were examined, and the accuracy, sensitivity and specificity of normal thyroid tissue was 80.99%, 93.66% and 76.06%, and the accuracy, sensitivity and specificity of sternocleidomastoid muscle tissue was 79.58%, 91.55%and 78.87% respectively. According to the normal thyroid tissue elasticity score, 121 cases were grade 0 - 2, 21 cases were grade 3 ~ 4;According to the sternocleidomastoid muscle tissue elasticity score, 119 cases were grade 0 - 2, 23 cases were grade 3 ~ 4（P〈0.05）. The elastic strain rate of the malignant nodules of the two species was higher than that of the benign nodules（P〉0.05）. No significant difference was found in the elastic strain rate between the two reference materials and malignant nodules（P〉0.05）. Conclusions Normal thyroid tissue and chest lock and papillary muscle can be used as reference objects in the differential diagnosis of benign and malignant thyroid tumor.

关 键 词：正常甲状腺组织 胸锁乳突肌 超声弹性成像 甲状腺肿瘤 鉴别 

分 类 号：R445.1[医药卫生—影像医学与核医学]