颈动脉狭窄行CAS后发生CHS的危险因素研究  

Risk Factors of Cerebral Hyperperfusion Syndrome Following Carotid Artery Stenting in Patients with Carotid Artery Stenosis

作　　者：李博生[1] 罗伟良[1] 刘武[1] 邓宇平[1] 朱晔宁[1] 

机构地区：[1]惠州市中心人民医院神经内科,广东惠州516008

出　　处：《临床医学工程》2016年第3期296-298,共3页Clinical Medicine & Engineering

摘　　要：目的探讨老年颈动脉狭窄患者行颈动脉支架置入术(CAS)后发生过度灌注综合征(CHS)的危险因素。方法选取本院2008年6月至2013年4月收治的230例老年颈动脉狭窄患者,均行CAS治疗,根据有无CHS分为无CHS组(n=221)和CHS组(n=9),对两组患者的一般资料进行比较,独立危险因素采用分层分析法分析。结果 CHS组患者糖尿病、术后高血压发生率显著高于无CHS组,两组比较差异有统计学意义(P<0.05);分层分析法分析结果显示,糖尿病(OR=4.822,P<0.05)、术后高血压(OR=6.466,P<0.05)是CAS术后出现CHS的重要危险因素。结论颈动脉狭窄患者中CAS术后高血压和术前糖尿病史患者更容易发生CHS,CHS患者预后较差,要采取多角度干预措施防控CHS发生。Objective To study the risk factors of cerebral hyperperfusion syndrome（CHS） following carotid artery stenting（CAS） in elderly patients with carotid artery stenosis. Methods A total of 230 cases of elderly patients with carotid artery stenosis admitted to our hospital from June 2008 to April 2013 were selected. All patients were treated with CAS. After CAS, 9 patients with CHS were set as the CHS group, while 221 patients without CHS were set as the non-CHS group. The general data of two groups were analyzed, and the independent risk factors were analyzed by stratified analysis. Results The incidences of diabetes, postoperative high blood pressure of CHS group were significantly higher than those of non-CHS group（P〈0.05）. Stratified analysis showed that diabetes（OR = 4.822, P〈0.05）,postoperative high blood pressure（OR = 6.466, P〈0.05） were the important risk factors of CHS after CAS. Conclusions Carotid artery stenosis patients with postoperative high blood pressure and preoperative diabetes are more likely to have CHS after CAS. CHS patients have poor prognosis, so comprehensive intervention measures should be taken to prevent and control the occurrence of CHS.

关 键 词：颈动脉狭窄 颈动脉支架置入术 过度灌注综合征 危险因素 

分 类 号：R543.5[医药卫生—心血管疾病]