椎管内肿瘤切除术后切口并发症的相关因素分析  

Analysis of factors related to surgical incision complications following intraspinal tumor resection

作　　者：吴玉仙[1] 纪玉清[1] 李建民[1] 李玉椿 王光辉[1] 程坤[1] 李振峰[2] 杨强[2] 

机构地区：[1]山东大学齐鲁医院(青岛)骨肿瘤科,山东青岛266035 [2]山东大学齐鲁医院骨肿瘤科

出　　处：《中国骨与关节损伤杂志》2016年第3期251-253,共3页Chinese Journal of Bone and Joint Injury

摘　　要：目的分析导致椎管内肿瘤切除术后切口并发症发生的危险因素。方法回顾性分析自2010-01—2013-12手术切除治疗的椎管内肿瘤88例,分为2组,无切口并发症组(70例)和有切口并发症组(18例)。统计分析2组相关因素:性别、年龄、肿瘤性质、有无糖尿病、有无肥胖、有无吸烟、有无激素应用史、有无手术史、术前是否放疗、术前是否化疗、手术时间、术中出血量、有无脑脊液漏、有无术后肢体及大小便功能障碍。结果单因素分析显示2组性别、年龄、肿瘤性质、有无糖尿病、有无肥胖、有无吸烟、有无激素应用史、有无手术史、术前是否放疗、术前是否化疗、术中出血量、有无术后肢体及大小便功能障碍这12项相关因素差异无统计学意义(P>0.05);2组手术时间、有无脑脊液漏2项相关因素差异有统计学意义(P<0.05)。将手术时间、脑脊液漏2项进一步行Logistic回归分析显示,脑脊液漏(P=0.012,OR=10.579)及手术时间>3 h(P=0.020,OR=6.593)是椎管内肿瘤术后切口并发症发生的危险因素。结论椎管内肿瘤切除术后切口并发症与术后脑脊液漏、手术时间>3 h明显相关,应引起足够重视。Objective To analyze risk factors for incision complications of intra-spinal canal tumor after operation. Methods Eighty eight cases of spinal tumors with surgical treatment from January 2010 to December 2013 were retrospectively analyzed, and they were divided into 2 groups： with incision complication group （70 cases） and without incision complication group（18 cases）. The related factors were analyzed,including their gender, age, nature of the tumor, the history of diabetes, obesity, smoking, hormone use, surgical treatment, radiotherapy, chemotherapy, operation time, intraoperative bleeding volume, cerebrospinal fluid leakage and postoperative limb and defecation dysfunction. Results Univariate analysis showed that between the two groups： there were no statistically significant differences in the history of diabetes, obesity, smoking, hormone use, surgical treatment, radiotherapy, chemotherapy, intraoperative bleeding volume, and postoperative limb and defecation dysfunction （P 〉0.05）; there were statistically significant differences in operation time, eerebrospinal fluid leakage（P 〈0.05）. Further logistic regression analysis showed that： cerebrospinal fluid leakage（P =0.012, OR =10.579） and long operation time （more than 3h）（P =0.020, OR =6.593） were the risk factors related to surgical incision complication following intraspinal tumor resection. Conclusion Surgical incision complications of intra-spinal canal tumor after operation are related to long operation time and postoperative cerebrospinal fluid leakage, which should be paid enough attention to.

关 键 词：椎管内肿瘤 手术切除 切口感染 脑脊液漏 危险因素 

分 类 号：R619[医药卫生—外科学]