脊柱嗜酸性肉芽肿23例治疗分析  

Clinical treatment of eosinophilic granuloma of the spine:an analysis of 23 cases

作　　者：魏任雄[1] 谢远龙[1] 邓洲铭[1] 蔡林[1] 

机构地区：[1]武汉大学中南医院骨科,430071

出　　处：《临床外科杂志》2016年第2期130-132,共3页Journal of Clinical Surgery

摘　　要：目的分析脊柱嗜酸性肉芽肿的临床治疗方法及疗效。方法脊柱嗜酸性肉芽肿患者23例,保守治疗9例,开放手术14例,其中微创手术5例。采用VAS疼痛评分及脊柱0DI评分评估手术治疗及保守治疗患者生活质量情况,并分析并发症及椎体高度恢复情况。结果患者治疗后疼痛明显缓解,脊柱功能得到改善,手术组与保守组患者0DI评分比较差异无统计学意义,但微创组椎体高度恢复值[(8.56±2.31)mm]高于开放手术组[(6.13±1.08)mm]及保守组[(6.74±0.99)mm],差异有统计学意义(P<0.05)。结论脊柱嗜酸性肉芽肿治疗方式需要遵循个体化原则,有明显神经症状及进行性畸形患者需手术治疗,微创手术更有利于椎体高度的恢复。Objective To evaluate the efficacy of clinical treatment on spinal eosinophilic granuloma. Methods A total of 23 cases of patients with eosinophilic granuloma of the spine were enrolled in the study,including conservative treatment in 9 cases and open surgery in 14 cases, of which 5 cases of minimally invasive surgery. VAS pain score and Oswestry disability index（ODI） was used to evaluate the efficacy surgical treatment. Complications and vertebral body height recovery were analyzed. Results After treatment the patients were relieved of pain, and spinal function was improved. There were no significant difference in ODI score between the groups, but minimally invasive surgical restoration [ （ 8.56 ± 2.31 ）mm ] in of vertebral height is higher than open surgery [ （6. 1 3±1.08 ） mm ] and conservative treatment [ （ 6.74 ± 0.99 ） mm ], the differences were statistically significant （ P 〈 0.05 ）. Conclusion The treatment of eosinophilic granuloma of the spine should follow the individualized principle. Patients with obvious neurological symptoms and progressive deformity need surgery and minimally invasive treatment could be more helpful in restoring vertebral height.

关 键 词：脊柱嗜酸性肉芽肿 保守治疗 微创手术 

分 类 号：R687.3[医药卫生—骨科学]