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作 者:林昭众 刘彦舜 陈永全 赖伟珍 张义森 罗华高 郭永强 谢珺田[2]
机构地区:[1]福建省永安市立医院疼痛科,永安366000 [2]山东省立医院疼痛临床中心,济南250021
出 处:《中国疼痛医学杂志》2016年第2期114-117,共4页Chinese Journal of Pain Medicine
基 金:福建省三明市科技局立项项目(项目编号:2011-C-9)
摘 要:目的探讨突出物靶点射频热凝复合神经根脉冲射频调节治疗腰椎间盘突出症的临床疗效及安全性。方法:选择60例主要表现为神经根炎的腰椎间盘突出症患者,随机分为试验组和对照组,每组30例。取得患者充分的知情同意并签字后,试验组采用突出物靶点射频热凝复合神经根脉冲射频调节治疗,对照组单纯采用突出物靶点射频热凝治疗,分别于术后当天、术后第3个月、第6个月、第12个月对患者进行随访,记录视觉模拟评分(visual analogue scale,VAS)及改良Mac Nab标准评估结果。所得数据资料以SPSS 13.0统计软件进行分析,P<0.05认为差异有统计学意义。结果:术前两组患者年龄、性别、病程、病变阶段、VAS评分比较无统计学差异(P>0.05)。与对照组相比,试验组术后当天及第3个月随访VAS减低,差异有统计学意义(P<0.05)。术后第3个月试验组疗效为优的病例数大于对照组,第6个月、第12个月试验组疗效为优和良的例数均大对照组(P<0.05)。两组均无明显的不良反应事件发生。结论:突出物靶点射频热凝复合神经根脉冲射频调节治疗以神经根炎为主要表现的腰椎间盘突出症临床疗效优于单纯突出物靶点射频热凝治疗方法。Objective: To evaluate the efficacy and the safety of targeted radiofrequency coagulation combined with pulsed radiofrequency modulation on heniated neucleus pulposus mainly marked by radiculitis. Methods: After adequate communication and informed consent, 60 patients diagnosed with heniated neucleus pulposus mainly marked by radiculitis were enrolled. All cases were randomly divided into 2 groups, combined procedures group(experimental group) and targeted radiofrequency coagulation group(control group), 30 cases in each. In control group, patients received targeted radiofrequency coagulation ohly; whereas in experimental group, patients received targeted radiofrequency coagulation combined with pulsed radiofrequency modulation. Follow-up by interview or telephone at 3, 6, and 12 months after discharge was recorded. The visual analogue scale was assessed, and the patient's outcome results were graded as excellent, good, fair, or poor based on the Mac Nab criteria with modification. Finally the data were analyzed with SPSS13.0 software(the significant level is defined as P〈0.05). Results: There were no significant differences between the two groups among age, gender, pathogenesis, pathological level, as well as the visual analogue scores(P〉0.05). Compared with the control group, patients in the experimental group reported lower visual analogue scores immediately and 3-month after procedures(P〈0.05). Meanwhile in the experimental group, the cases assessed as excellent at 3 rd month, the cases assessed as both excellent and good at 6-month and 12-month after procedures were more than those in the control group(P〈0.05). Conclusion: Targeted radiofrequency coagulation combined with pulsed radiofrequency modulation is superior to targeted radiofrequency only for heniated neucleus pulposus mainly marked by radiculitis.
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