复方黄芩溶液湿敷治疗带状疱疹疗效观察  

Clinical Efficacy Observation of Herpes Zoster Treated by Compound Radix Scutellariae Solution Wet Application

作　　者：王佳[1] 孙桂芹[2] 马丽俐[3] 

机构地区：[1]浙江中医药大学第一临床医学院,杭州310053 [2]浙江中医药大学医学技术学院 [3]浙江中医药大学附属第一医院

出　　处：《浙江中医药大学学报》2016年第2期134-136,149,共4页Journal of Zhejiang Chinese Medical University

基　　金：浙江省中医药科技计划项目(2015ZB041)

摘　　要：[目的]观察复方黄芩溶液湿敷治疗带状疱疹的临床疗效。[方法]将50例患者随机分为复方黄芩组25例和呋喃西林组25例,分别予复方黄芩溶液、呋喃西林溶液湿敷,同时均予静滴更昔洛韦0.3g/次,1次/d,口服维生素B1片20mg/次,3次/d,口服甲钴胺片0.5mg/次,3次/d,1周为1疗程。记录治疗前及疗程第3、5、7d所有患者疼痛、皮损评分及记录疱疹停发、水疱干涸、水疱开始结痂及结痂面积≥50%时间。[结果]复方黄芩组对疼痛、皮损评分的降低明显优于呋喃西林组,其疱疹停发、水疱干涸、开始结痂以及结痂面积≥50%时间均较呋喃西林组提前,差异有统计学意义(P<0.05)。[结论]复方黄芩溶液治疗带状疱疹临床疗效显著,在缓解疼痛、促进皮损消退等方面具有显著的优越性。[Objective]Observe clinical efficacy of herpes zoster treated by the compound radix scutellariae solution wet application.[Method]50 patients were randomly divided into 25 cases of the compound radix scutellariae group and 25 cases of the nitrofurazone group, respectively given wet application of the compound radix scute-Uariae solution and nitrofurazone solution, at the same time given intravenousganciclovir 0.3g/time, l time/d, oral vitamin B1 20mg/time, 3 times/d, oral cobalt amine 0.5mg/time, 3 times/d, one week as a period. Record all patients＂ pain, skin lesion scores before the treatment and in the course of the third, fifth, seventh day and record the time of herpes stopping hair, blister drying up, blister beginning to scab and the scabby area not less than 50%.[Result] Pain, skin lesion scores of the compound radix scutellariae group were signifycantly lower than those of nitrofurazane group, the time of herpes stopping hair, blister drying up, blister beginning to scab and the scabby area not less than 50% of the compound radix scutellariae group compared with nitrofurazone group in advance, the difference was statistically significant（P〈0.05）. [Conclusion]Treatment of the compound radix scutellariae solution to herpes zoster had distinct clinical efficacy, having significant advantages in terms of alleviating pain and promoting skin lesions subsided.

关 键 词：带状疱疹 复方黄芩溶液 神经痛 疼痛评分 皮损评价 

分 类 号：R591[医药卫生—内科学]