均匀设计法优选金银花水提液絮凝工艺的研究  

Study on the technology of flocculation of water-extraction solution in Lonicerae Japonicae Flos by uniform design method

作　　者：叶思勇[1] 魏霞[1] 陈智[2] 

机构地区：[1]济南市第二人民医院药剂科,250001 [2]山东中医药大学药学院,济南250355

出　　处：《国际中医中药杂志》2016年第3期247-249,共3页International Journal of Traditional Chinese Medicine

摘　　要：目的采用均匀设计方法优选金银花水提液的絮凝工艺。方法分别以药液浓缩比例、壳聚糖用量、絮凝液温度、絮凝液pH值4个因素为考察对象，以沉淀比和有效部位转移率为指标，采用均匀设计u6（6。）优选金银花水提液的絮凝工艺。结果确定壳聚糖用量O．14％，絮凝液pH值为6，药液浓缩比例至1：3，絮凝温度30℃为最佳絮凝工艺。结论本絮凝工艺纯化效果良好，可代替传统的醇沉工艺。Objective To study the technology of flocculation of water-extraction solution in Lonicerae Japonicae Flos by uniform design method. Methods The liquid concentration ratio, chitosan dosage, temperature and pH were studied with the ratio of the precipitation and the rate of the transformation of valid target as index. Results The optimal flocculation process was： dosage of ehitosan was 0.14%, pH was 6, the concentration of the solution was 1：3 and the temperature was 30 ℃. Conclusions The effect of purification is good, and the fiocculation process can replace the traditional precipitation process.

关 键 词：均匀设计 絮凝 金银花 

分 类 号：TQ28[化学工程—有机化工]