聚乙交酯-丙交酯-己内酯三元无规共聚物及其电纺膜的制备与表征  

Preparation and Characterization of Poly( lactide-co-glycolide-co-caprolactone) s Random Terpolymer and Their Electrospun Membrane

作　　者：杨欢[1,2] 黄冬玲[1,2] 陈栋梁[1] 熊成东[1] 张琦[3] 庞秀炳 熊左春[1] 

机构地区：[1]中国科学院成都有机化学研究所,四川成都610041 [2]中国科学院大学,北京100049 [3]浙江省人民医院临床医学研究所,浙江杭州310014 [4]浙江省生物可降解医用材料工程技术研究中心,浙江东阳322118

出　　处：《合成化学》2016年第3期243-246,共4页Chinese Journal of Synthetic Chemistry

基　　金：中国科学院西部之光资助项目

摘　　要：以左旋丙交酯、乙交酯和己内酯为原料,辛酸亚锡为催化剂,在真空条件下经本体熔融开环聚合,制备了三元无规共聚物(P),其结构和性能经1H NMR,IR,DSC和粘度表征。实验结果表明:P的玻璃化转变温度可通过单体的投料比调控;采用静电纺丝法可方便地获得共聚物亚微米纤维膜。Random terpolymers（ P） of L-lactide,glycolide and caprolactone had been prepared by bulk ring-opening copolymerization initiated by stannous octoate under high vacuum. The structures and properties had been investigated by1 H NMR,IR,DSC and viscosimetry. The results indicated that the glass transition temperature of P can be controlled by adjusting the monomer ration. The submicron fiber membrane of P can be obtained easily through electrospinning.

关 键 词：三元共聚物 熔融共聚 制备 玻璃化转变温度 电纺 

分 类 号：O633.14[理学—高分子化学]