422例终止妊娠的梅毒患者既往随访结果分析  

Follow- up Analysis on the Pregnancy Termination in 422 Patients with Syphilis

作　　者：鲁东平[1] 鲁菊香 秦琴[3] 付敏 张荣[1] 李湘辉[1] 贾婕[1] 

机构地区：[1]深圳市宝安区慢性病防治院皮肤科,广东深圳518133 [2]广州市越秀区儿童医院,广东广州510115 [3]深圳市宝安区人民医院皮肤科,广东深圳518133 [4]深圳市宝安区沙井人民医院,广东深圳518104

出　　处：《皮肤性病诊疗学杂志》2016年第1期8-12,共5页Journal of Diagnosis and Therapy on Dermato-venereology

基　　金：2015年宝安区科技计划社会公益(医疗卫生类)项目(编号:2015336)

摘　　要：目的：对深圳市宝安区终止妊娠的梅毒患者的随访结果进行分析,为有针对性地开展梅毒预防与控制工作提供依据。方法：收集宝安区终止妊娠的422例梅毒患者的相关资料,并进行回顾性分析。结果：422例终止妊娠的梅毒患者中20-35岁女性357例（84.60%）;经婚前性传播者194例（45.97%）,婚内性传播81例（19.19%）,婚外性传播32例（7.58%）;潜伏梅毒321例（76.07%）;422例终止妊娠的梅毒患者中人工流产者187例（44.31%）,其中初筛TRUST滴度≤1∶4者129例（30.57%）;自然流产者35例（8.29%）,其中初筛TRUST滴度≤1∶4者22例（5.21%）;死胎死产者63例（14.93%）,其中初筛TRUST滴度≥1∶8者53例（12.56%）;异位妊娠者137例（32.46%）,其中初筛TRUST滴度≤1∶4者106例（25.12%）。378例患者（89.57%）在孕28周之前进行梅毒筛查,其中352例患者（83.41%）选择苄星青霉素治疗。69.43%的患者6个月后就失访,极少数（1.9%）终止妊娠的梅毒患者随访到两年。结论：加强梅毒孕产妇的管理对降低梅毒患者终止妊娠发生率有重要意义。Objective：To analyze the follow up results of pregnancy termination in syphilis patients in Bao＇an District, and to provide evidences for the prevention and control measures toward syphilis. Methods：422 cases of pregnancy termination in syphilis patients were collected in Bao＇ an district, and were analyzed retrospectively. Results：84.60% syphilis patients with termination of pregnancy were between the age of 20 to 35 years old ; 45.97% syphilis patients were premarital sexual transmission, marital sexual transmission accounted for 19. 19%, extramarital sexual trans- mission accounted for 7.58% ; 76.07% patients had latent syphilis. Artificial abortion accounted for 44. 31%, 30. 57% patients of them had TRUST titer ≤1：4; 8.29% patients had spontaneous abortion, and 5.21% of them also had TRUST titer ≤ 1：4; stillbirth were 14.93%, and 12.56% of them had TRUST titer ≥1：8 ; ectopic pregnancy accounted for 32.46%, and 25.12% of them had TRUST titer ≤1： 4. The majority of patients （89.57%） have received syphilis screening before 28 weeks, and most of the patients （83.41%） received benzathine penicillin treatment;69.43% of the patients were lost to follow-up after 6 months, very few （1.9%） syphilis patients with pregnancy termination were followed-up for two years. Conelusion：h is necessary to improve the management of pregnant women with syphilis, of pregnancy termination in syphilis patients. which has great significance in reducing the rate

关 键 词：终止妊娠 梅毒 随访 

分 类 号：R759.15[医药卫生—皮肤病学与性病学]