剖宫产术后1年内中期妊娠应用米非司酮联合米索前列醇药物引产的效果  

Effect of Mifepristone Combined with Misoprostol on Induction of Labor in 1 Year after Cesarean Section

作　　者：梅立群 

机构地区：[1]四川省眉山市妇幼保健院妇产科,四川眉山620000

出　　处：《河北医学》2016年第3期453-456,共4页Hebei Medicine

基　　金：四川省卫生厅科研课题;(编号:14ZA0192)

摘　　要：目的:探讨米非司酮联合米索前列醇药物引产在剖宫产术后1年内中期妊娠引产中的应用效果及安全性。方法:将剖宫产术后1年内中期妊娠自愿要求引产的24例孕妇将其作为观察组,另选取同期住院的剖宫产术后2年以上的中期妊娠自愿要求引产的孕妇30例作为对照组。两组均给予米非司酮联合米索前列醇进行药物引产,观察比较两组孕妇引产效果。结果:两组孕妇引产成功率、口服米索前列醇总量、口服米索前列醇至胎儿娩出时间、阴道流血量、住院时间、胎盘残留及宫颈裂伤发生率比较差异均不具显著性(P>0.05)。结论:剖宫产术后1年内中期妊娠应用米非司酮联合米索前列醇药物引产临床效果显著,安全可靠,值得临床推广。Objective： To investigate the effect and safety of mifepristone combined with misoprostol in the induction of labor in 1 year after cesarean section. Method： 24 pregnant women who volunteered for labor in the middle of the 1 year after the operation of our hospital cesarean section were observed as the observation group,another 2 years of hospitalization in the same period in the years after the mid pregnancy induced labor in the middle of the 30 cases of pregnant women as a control group. The two groups were given mifepristone combined with misoprostol for induction of labor,observation and comparison of the effect of two groups of pregnant women. Result： Two groups of pregnant women abortion success rate,oral misoprostol total,oral misoprostol to fetus delivery time,the amount of vaginal bleeding,hospitalization time,placenta residue and cervical laceration difference in the incidence rate were not significant（ P〈0. 05）. Conclusion： The clinical effect of mifepristone combined with misoprostol in the treatment of 1 years after cesarean section is significant,safe and reliable,it is worthy of clinical promotion.

关 键 词：米非司酮 米索前列醇 剖宫产 中期妊娠 引产 

分 类 号：R719.3[医药卫生—妇产科学]