清热解毒活血法对不稳定型心绞痛患者颈动脉斑块易损斑块的影响  

Effective of the Qingre Jiedu Huoxue therapy on the vulnerable plaque in patients with unstable angina

作　　者：马哲河 吴懿 刘景 

机构地区：[1]广州市海珠区石溪中医医院,广东广州510288

出　　处：《中医临床研究》2016年第8期19-20,共2页Clinical Journal Of Chinese Medicine

基　　金：广东省中医药管理局2013年科研基金项目资助项目(编号:20131011)

摘　　要：目的:探讨清热解毒活血法对不稳定型心绞痛患者颈动脉斑块易损斑块的影响。方法:将60例不稳定型心绞痛患者按随机数字表分为对照组(常规西药治疗)和治疗组(常规西药治疗基础上加用清热解毒活血方),治疗周期为4周。主要观察两组治疗前后心绞痛发作、中医证候的变化以及IMT、Crouse积分的变化。结果:对照组与治疗组心绞痛缓解总有效率分别为70.00%和90.00%,中医症状疗效总有效率分别为66.67%和90.00%,治疗组与对照组比较有显著性差异(P<0.05);治疗后,治疗组患者IMT、Crouse积分较对照组显著减少(P<0.05)。结论:清热解毒活血法治能有效改善不稳定型心绞痛的临床症状,并稳定易损斑块,是安全、有效的辅助治疗药物。Objective To investigate efficacy of the Qingre Jiedu Huoxue therapy on vulnerable plaque in patients with unstable angina.Methods： 60 patients with unstable angina were randomly divided into two groups. The control group was treated with routine western medicine;and the treatment group was treated by the Qingre Jiedu Huoxue therapy, 4 weeks as a course. Angina relief, symptoms score, IMT score andCrouse score in two groups were observed. Results： The efficiency of angina relief was 70.00% in the control group, and 90.00% in the treatmentgroup. The efficiency of TCM symptom score was 66.67% in the control group, and 90.00% in the treatment group. In treatment, IMT and Crousescores in two groups were decreased significantly. The differences were statistically significant （P〈0.05）. Conclusion： The Qingre Jiedu Huoxuetherapy on the vulnerable plaque in patients with unstable angina shows a good effect.

关 键 词：不稳定型心绞痛 颈动脉易损斑块 清热解毒活血 临床疗效 

分 类 号：R541.4[医药卫生—心血管疾病]