正常孕产妇剖宫产分娩前后全血细胞参数的变化分析  

Physiological Changes in Hematological Parameters of Normal Pregnant Women before and after Cesarean Delivery

作　　者：李星[1] 常颖[2] 陈叙[2] 

机构地区：[1]天津医科大学,300070 [2]天津市中心妇产科医院

出　　处：《国际妇产科学杂志》2016年第1期32-35,共4页Journal of International Obstetrics and Gynecology

摘　　要：目的：建立本院正常孕产妇剖宫产分娩前和分娩后24 h内全血细胞参数的参考值范围,并分析其变化。方法：选取2015年6—10月在天津市中心妇产科医院产科行剖宫产分娩的健康足月孕产妇为研究对象,回顾性分析产妇分娩前和分娩后24 h的血常规结果,对2组数据进行统计学分析。结果：纳入经剖宫产分娩的正常产妇506例,分娩前红细胞（RBC）参考值范围（3.27~4.49）×1012/L,血红蛋白（Hb）和红细胞压积（HCT）的参考值范围分别为93.4~135.3 g/L、0.286~0.399,白细胞（WBC）计数的参考值范围为（5.47~12.34）×109/L,血小板（PLT）计数的参考值范围为（113.7~307.0）×109/L;分娩后RBC显著下降（P=0.002）,Hb和HCT无显著变化,平均红细胞体积（MCV）、平均红细胞血红蛋白量（MCH）和平均红细胞血红蛋白浓度（MCHC）轻度增加,WBC计数增加（P=0.000）,中性粒细胞百分比和中间细胞百分比增加（P=0.000）,淋巴细胞百分比下降（P=0.000）,PLT计数下降（P=0.000）。结论：健康产妇的血红蛋白、血小板参考值范围与非孕女性的参考值范围存在一定差异,与分娩前相比,分娩后WBC计数升高,而RBC计数和PLT计数下降,因此有必要制定针对中国女性孕期和产后血细胞参数的正常参考值范围。Objective：To establish the reference intervals for hematologic parameters in antepartum and 24 hours after postpartum in healthy pregnant women, and analyze physiological changes occurring in hematologic parameters. Methods： The samples comprised of healthy pregnant women who had cesarean section at term in Tianjin Central Hospital of Gynecology Obstetrics from Jun. 2015 to Oct. 2015. The blood test results before and after delivery were retrospectively analyzed. Results：The reference intervals obtained before delivery were： RBC,（3.27~4.49）×1012/L; Hb, 93.4~135.3 g/L; HCT, 0.286~0.399; WBC,（5.47~12.34）×109/L; PLT,（113.7~307.0）×109/L. After delivery, RBC count and PLT dropped significantly（P=0.002, P=0.000,respectively）, and WBC count increased significantly（P=0.000）, Hb and HCT levels remained unchanged, and the value of MCV,MCH, MCHC slightly increased, the percentage of neutrophils and intermediate cells increased significantly（ P=0.000）, while the percentage of lymphocytes dropped significantly（P=0.000）. Conclusions： The reference intervals for Hb concentration and PLT in healthy prgnant women showed some differences with non-pregnant women. Compared with antepartum, the WBC count increased after delivery, while the RBC count and PLT count dropped. The differences observed underscore the need to establish reference values for Chinese women before and after delivery.

关 键 词：妊娠 剖宫产术 分娩 全血细胞参数 参考值范围 

分 类 号：R719.8[医药卫生—妇产科学]