心脏磁共振成像评价缺血性心力衰竭心肌纤维化研究进展及应用  

Research progresses and applications of cardiac MR in myocardial fibrosis of ischemic heart failure

作　　者：陈榆舒 陈伟[1] 郑捷[1] 郜发宝[1] 

机构地区：[1]四川大学华西医院放射科,四川成都610041

出　　处：《中国医学影像技术》2016年第3期449-452,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金重点项目(81130027);国际(地区)合作与交流项目(81520108014)

摘　　要：心肌纤维化(MF)是缺血性心肌病发展至心力衰竭的重要中间环节。目前,检测MF存在较大困难,心肌活检虽然是检测MF的金标准,但精确度较低,并有一定致残、致死风险。心脏MR(如LGE、T1mapping及近期出现的T1ρ技术)可无创量化评价MF,为临床评估和干预MF提供重要技术支持。本文对心脏MR技术在缺血性心力衰竭MF中的研究进展及应用进行综述。Myocardial fibrosis（MF）has already been recognized as the fundamental process in the pathogenesis of ischemic heart failure（IHF）.The detection of MF is difficult at present.The gold standard of MF is myocardial biopsy,but it has low accuracy and certain risk of disability and death.Cardiac MR（CMR）can be used to evaluate the MF noninvasively and quantitatively,such as late-gadolinium enhancement,T1 mapping and T1ρ,which is an important technology for clinical assessment and intervention of MF.The research progresses and applications of CMR in MF of ischemic heart failure were reviewed in this article.

关 键 词：心力衰竭 心肌纤维化 磁共振成像 

分 类 号：R542.23[医药卫生—心血管疾病] R445.2[医药卫生—内科学]