股骨干骨折并发下肢深静脉血栓形成的危险因素研究  

Risk factors of lower limb deep vein thrombosis in patients with femoral shaft fracture

作　　者：葛波涌[1] 王玉波[1] 丁丽[1] 王明太[1] 

机构地区：[1]郑州大学第二附属医院急诊科,450014

出　　处：《中华实验外科杂志》2016年第3期817-819,共3页Chinese Journal of Experimental Surgery

摘　　要：目的探讨股骨干骨折并发下肢深静脉血栓（DVT）形成的危险因素。方法收集分析我院57例股骨干骨折患者基础临床资料，采用多层螺旋CT静脉造影术对所有患者进行下肢DVT筛查。依据筛查结果将患者分为DVT组和非DVT组。对两组患者的年龄、性别、是否存在合并伤、原发性高血压史、糖尿病史、D-二聚体水平等进行统计分析，并采用多因素Logistic回归分析股骨干骨折并发下肢DVT的危险因素。结果57例股骨干骨折的患者中，DVT的总发生率为24．6％（14／57），骨折合并伤、原发性高血压、糖尿病以及D-二聚体水平升高患者中DVT发生率分别为57．1％、78．6％、28．6％、85．7％，且分布差异均有统计学意义（P〈0．05）。多因素Logistic回归分析显示，合并伤、原发性高血压、糖尿病以及D-二聚体水平升高是股骨干骨折患者并发DVT的独立危险因素（P〈0．05）。结论合并伤、原发性高血压、糖尿病以及D-二聚体水平升高是股骨干骨折患者并发DVT的独立危险因素，患者应密切监测血栓形成，及时采取相应预防措施。Objective To analyze the risk factors of lower limb deep vein thrombosis （DVT） in patients with femoral shaft fracture. Methods A retrospective study was conducted to analyze the 57 pa- tients with femoral shaft fracture in our department from January 2011 to January 2015. DVT was detected by direct multislice spiral CT venography. According to the results, the patients were divided into DVT group and DVT - free group. The data were analyzed concerning general clinical information, associated in- jury, primary hypertension, diabetes, D - dimer level. The risk factors of DVT were determined using Lo- gistic regression analysis. Results DVT occurred at the lower extremity in 24. 6% （ 14/57 ） of 57 pateints. The incidence of associated injury, primary hypertension, diabetes and D - dimer levels were 57. 1% , 78.6% , 28.6% and 85.7% respectively, and they were identified as the independent risk fac- tors associated with DVT （ P 〈 0.05 ）. Conclusion The main risk factors of lower limb DVT in patients with femoral shaft fracture were associated injury, primary hypertension, diabetes and D - dimer level.

关 键 词：股骨骨折 深静脉血栓 危险因素 

分 类 号：R543.6[医药卫生—心血管疾病]