细菌性阴道病合并其他妇科感染性疾病的临床研究  

Clinical characteristics of bacterial vaginosis patients complicated with other gynecological infectious diseases

作　　者：王增艳[1] 刘正玲[1] 孙金霞[1] 闫华[1] 许宗兰[1] 

机构地区：[1]临沂市沂水中心医院妇科,山东临沂276400

出　　处：《中华医院感染学杂志》2016年第6期1382-1384,共3页Chinese Journal of Nosocomiology

基　　金：山东省自然科学基金资助项目(2014ZRE27286)

摘　　要：目的探讨细菌性阴道病合并其他妇科感染性疾病患者的临床特点,为临床治疗提供依据。方法通过分析2013年5月-2015年4月医院收治的126例细菌性阴道病合并其他妇科感染性疾病患者临床资料,随机分为观察组和对照组各63例,观察组患者给予甲硝唑联合维生素C治疗,对照组患者给予甲硝唑单药治疗,疗程结束后观察两组临床疗效差异;采用SPSS 11.0软件进行统计分析。结果统计两组细菌性阴道病患者阴道分泌物中病原体种类及混合感染类型,患者感染解脲脲病原体比率最高,占32.54%;患者感染病原体类型以细菌+酵母菌属混合感染的比例较高;患者合并妇科病类型中盆腔炎所占比例最高,为48.41%;治疗痊愈率为55.56%,临床有效率为90.48%,显著高于对照组的痊愈率39.68%和临床有效率68.25%,差异有统计学意义(P<0.05)。结论细菌性阴道病合并其他感染性妇科疾病患者采用甲硝唑联合维生素C治疗临床疗效显著,病情转归显著,值得临床推广。OBJECTIVE To explore the clinical characteristics of bacterial vaginosis patients complicated with other gynecological infectious diseases so as to provide guidance for clinical treatment.METHODS A total of 126 bacterial vaginosis patients complicated with other gynecological infectious diseases who were treated in the hospital from May 2013 to Apr 2015 were enrolled in the study and randomly divided into the observation group and the control group,with 63 cases in each,and the clinical data of the enrolled patients were analyzed.The observation group was treated with metronidazole combined with vitamin C,while the control group was given single metronidazole.The clinical efficacy was observed and compared between the two groups of patients after the treatment,and the statistical analysis was performed with the use of SPSS 11.0software.RESULTS The statistical analysis of the species of pathogens isolated from vaginal secretions an the types of mixed infections in the two groups of bacterial vaginosis patients showed that the patients with Ureaplasma urealyticum infection accounted for 32.54%,and the proportion of the patients with mixed bacterial and yeast infections was high.Among the patients complicated with gynecological diseases,48.41% had pelvic inflammatory disease.The cure rate of the observation group was55.56%,significantly higher than 39.68% of the control group;the effective rate of clinical treatment of the observation group was 90.48%,significantly higher than 68.25% of the control group（P0.05）.CONCLUSION The metronidazole combined with vitamin C can achieve significant clinical effect on treatment of the bacterial vaginosis patients complicated with other gynecological diseases,with the disease outcome remarkable,and it is worthy to be promoted in the hospital.

关 键 词：细菌性阴道病 妇科感染 临床分析 

分 类 号：R711.3[医药卫生—妇产科学]