患儿TORCH-IgM检测结果分析  

Detection of TORCH-IgM in children

作　　者：宋晓妍[1] 孟祥颖[1] 杜红梅[1] 牛超[1] 杨博[1] 贾莉婷[1] 

机构地区：[1]郑州大学第三附属医院检验科,河南郑州450052

出　　处：《中华医院感染学杂志》2016年第6期1385-1386,1389,共3页Chinese Journal of Nosocomiology

基　　金：河南省科技厅重点科研团队基金资助项目(B20140269)

摘　　要：目的调查分析0~1岁患儿TORCH-IgM感染状况及特点,为临床诊断及治疗提供理论参考。方法选择2014年5-11月收治的1 754例≤1岁患儿为研究对象,采用化学发光法检测患儿血清TORCH-IgM抗体,分析该年龄段患儿TORCH-IgM感染状况及特点,并探讨感染与月龄及临床疾病类型之间的关系,研究数据采用SPSS17.0软件进行统计分析。结果 1 754例患儿血清中TORCH-IgM阳性266例,阳性率为15.17%,其中人巨细胞病毒（HCMV）-IgM、单纯疱疹病毒（HSV）-IgM、风疹病毒（RV）-IgM和弓形虫（TOX）-IgM阳性率分别为8.72%、3.82%、2.79%和0.06%;4例患儿合并两种病原体感染,感染率为0.23%;TORCH阳性患儿临床疾病以婴儿肝炎综合征、黄疸、上呼吸道感染、支气管肺炎、发热待查及脑损伤综合征等为主。结论 0~1岁患儿TORCH感染较普遍,以HCMV感染为主,TOX感染罕见,并存在合并感染。OBJECTIVE To investigate the prevalence of TORCH-IgM infection in children aged from 0to 1year old and analyze the characteristics so as to provide theoretical basis for clinical diagnosis and treatment.METHODS A total of 1 754 children aged no more than 1year old who were treated in the hospital from May 2014 to Nov 2014 were recruited as the study objects,then the serum TORCH-IgM antibody was detected by using chemiluminescence method,the prevalence and characteristics of the TORCH-IgM infection in this age group of children were observed,the correlation between the infection and the month of age as well as the types of clinical diseases were explored,and the statistical analysis of data was performed with the use of SPSS17.0software.RESULTS The serum TORCH-IgM was detected positive in 266 of 1 754 children,with the positive rate 15.17%;the positive rates of human cytomegalovirus（HCMV）-IgM,herpes simplex virus（HSV）-IgM,rubella virus（RV）-IgM,and toxoplasma（TOX）-IgM were 8.72%,3.82%,2.79%,and 0.06%,respectively.Totally 4children were complicated with infections with two species of pathogens,with the infection rate 0.23%.The major clinical diseases in the TORCH-positive children included the hepatitis syndrome,jaundice,upper respiratory tract infection,bronchopneumonia,fever of unknown origin,and cerebral injury syndrome.CONCLUSIONThe TORCH infection is prevalent in the children aged from 0to 1year old,the HCMV infection is dominant,the TOX infection is rare,and the concurrent infection exists.

关 键 词：TORCH感染 患儿 人巨细胞病毒 

分 类 号：R373[医药卫生—病原生物学]