Novel wavelet neural network algorithm for continuous and noninvasive dynamic estimation of blood pressure from photoplethysmography  

作　　者：Peng LI Ming LIU Xu ZHANG Xiaohui HU Bo PANG Zhaolin YAO Hongda NHEN 

机构地区：[1]State Key Laboratory on Integrated Optoelectronic, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China

出　　处：《Science China(Information Sciences)》2016年第4期90-99,共10页中国科学（信息科学）（英文版）

基　　金：supported by National Basic Research Program of China (973) (Grant No. 2011CB933203);National Natural Science Foundation of China (Grant Nos. 61474107, 61372060, 61335010, 61275200, 61178051, 81300803);National High-Tech Research & Development Program of China (863) (Grants No. 2014AA032901);Grant for Capital Clinical Application Research with Characteristics (Grants No. Z141107002514061)

摘　　要：This paper proposes a novel wavelet neural network algorithm for the continuous and noninvasive dynamic estimation of blood pressure（BP）. Unlike prior algorithms, the proposed algorithm capitalizes on the correlation between photoplethysmography（PPG） and BP. Complete BP waveforms are reconstructed based on PPG signals to extract systolic blood pressure（SBP） and diastolic blood pressure（DBP）. To improve the robustness, Daubechies wavelet is implemented as the hidden layer node function for the neural network. An optimized neural network structure is proposed to reduce the computational complexity. Further, this paper investigates an inhomogeneous resilient backpropagation（IRBP） algorithm to calculate the weight of hidden layer nodes. The IRBP improves the convergence speed and reconstruction accuracy. Multiparameter intelligent monitoring in Intensive Care（MIMIC） databases, which contain a variety of physiological parameters captured from patient monitors, are used to validate this algorithm. The standard deviation σ between reconstructed and actual BP signals is 4.4797 mm Hg, which satisfies the American National Standards of the Association for the Advancement of Medical Instrumentation. The reconstructed BP waveform can be used to extract the SBP and DBP, whose standard deviations σ are 2.91 mmHg and 2.41 mmHg respectively.This paper proposes a novel wavelet neural network algorithm for the continuous and noninvasive dynamic estimation of blood pressure（BP）. Unlike prior algorithms, the proposed algorithm capitalizes on the correlation between photoplethysmography（PPG） and BP. Complete BP waveforms are reconstructed based on PPG signals to extract systolic blood pressure（SBP） and diastolic blood pressure（DBP）. To improve the robustness, Daubechies wavelet is implemented as the hidden layer node function for the neural network. An optimized neural network structure is proposed to reduce the computational complexity. Further, this paper investigates an inhomogeneous resilient backpropagation（IRBP） algorithm to calculate the weight of hidden layer nodes. The IRBP improves the convergence speed and reconstruction accuracy. Multiparameter intelligent monitoring in Intensive Care（MIMIC） databases, which contain a variety of physiological parameters captured from patient monitors, are used to validate this algorithm. The standard deviation σ between reconstructed and actual BP signals is 4.4797 mm Hg, which satisfies the American National Standards of the Association for the Advancement of Medical Instrumentation. The reconstructed BP waveform can be used to extract the SBP and DBP, whose standard deviations σ are 2.91 mmHg and 2.41 mmHg respectively.

关 键 词：photoplethysmogram（PPG） blood pressure（BP） Daubechies wavelet neural network inhomogeneous resilient backpropagation（IRBP） 

分 类 号：TP183[自动化与计算机技术—控制理论与控制工程] TN912.3[自动化与计算机技术—控制科学与工程]