血清肿瘤标志物在卵巢癌早期诊断中的临床价值  

Clinical value of serum tumor markers in the early diagnosis of ovarian cancer

作　　者：陈藕景[1] 祝莹[1] 

机构地区：[1]台州医院妇产科,浙江台州317000

出　　处：《中国性科学》2016年第3期48-50,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨血清肿瘤标记物中癌胚抗原(CEA)、甲胎蛋白(AFP)、糖类抗原125(CA125)、糖类抗原153(CA153)及糖类抗原199(CA199)在卵巢癌早期诊断中的应用价值。方法:以210例疑似卵巢癌患者作为研究对象,以病理学检查结果作为卵巢癌确诊标准,分别对CEA、AFP、CA125、CA153及CA199检查指标对卵巢癌诊断的灵敏性、特异性及诊断价值进行分析。结果:本研究中共有150例确诊为卵巢癌。而CEA、AFP、CA125、CA153及CA199检查在卵巢癌诊断中,以CA125的灵敏性及特异性最高。同时,在所观察的血清肿瘤标记物中,以CA125检查对卵巢癌的诊断价值最高。结论:血清CA125可作为早期卵巢癌的诊断标记物,对提高早期卵巢癌的诊断效果具有重要的应用价值。Objectives： To investigate the clinical value of serum tumor markers of carcinogenicity antigen（ CEA）,alpha- protein（ AFP）,carbohydrate antigen 125（ CA125）,carbohydrate antigen 153（ CA153） and sugar antigen 199（ CA199） in the early diagnosis of ovarian cancer. Methods： 210 cases of suspected ovarian cancer were selected as research subjects. Pathological diagnosis of ovarian cancer was used as a result of the standard. Respectively,analysis of indicators of sensitivity,specificity and diagnostic value among CEA,AFP,CA125,CA153 and CA199 in ovarian cancer diagnostic was done. Results： In this study,a total of 150 cases were diagnosed as ovarian cancer. Among CEA,AFP,CA125,CA153 and CA199 in the diagnosis of ovarian cancer,CA125 had the highest sensitivity and specificity. Meanwhile,in the serum tumor markers,CA125 had the highest diagnosis value. Conclusions： Serum CA25 can be used as a diagnostic marker for early diagnosis of ovarian cancer,which has important application value in the diagnosis of early ovarian cancer.

关 键 词：血清肿瘤标记物 卵巢癌 早期诊断 

分 类 号：R737.31[医药卫生—肿瘤]