枯草杆菌二联活菌颗粒、蒙脱石散与茵栀黄口服液联合辅助治疗新生儿黄疸的疗效观察  

Observation on Efficacy of Medilac-vita,Montmorillonite Powder and Yinzhihuang Oral Liquid in Adjuvant Treatment of Neonatal Jaundice

作　　者：白琼丹[1] 张璋[1] 

机构地区：[1]郑州市儿童医院新生儿内科,河南郑州450000

出　　处：《中国医院用药评价与分析》2016年第2期162-164,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨枯草杆菌二联活菌颗粒、蒙脱石散与茵栀黄口服液联合辅助治疗新生儿黄疸的临床疗效。方法:选取郑州市儿童医院2013年4月—2015年3月收治的新生儿黄疸92例,按随机数字表法分为2组各46例。对照组患儿给予蓝光照射为主的基础治疗,观察组患儿在对照组治疗基础上联合枯草杆菌二联活菌颗粒、蒙脱石散与茵栀黄口服液进行治疗。对2组患儿的临床疗效及其治疗前、后胆红素变化情况,治疗时间进行比较。结果:观察组患儿总有效率为97.8%,优于对照组的82.6%,2组的差异有统计学意义(P<0.05);观察组患儿总胆红素水平为(75.3±12.3)μmol/L,低于对照组的(98.8±19.2)μmol/L,2组的差异有统计学意义(P<0.05);观察组患儿治疗时间为(4.7±1.3)d,低于对照组的(7.8±2.5)d,2组的差异有统计学意义(P<0.05)。结论:枯草杆菌二联活菌颗粒、蒙脱石散与茵栀黄口服液联合辅助治疗新生儿黄疸,疗效显著,能够有效促进患儿总胆红素水平的降低,建议在临床上进一步推广。OBJECTIVE： To investigate the clinical efficacy of medilac-vita, montmorillonite powder and yinzhihuang oral liquid in adjuvant treatment of neonatal jaundice.METHODS： 92 cases with neonatal jaundice admitted into Children＇s Hospital of Zhengzhou from Apr.2013 to Mar.2015 were selected to be divided into two groups via the random number table,with 46 cases in each.The control group mainly received blue light irradiation for basic treatment,while the observation group were additionally treated with medilac-vita,montmorillonite powder and yinzhihuang oral liquid.The clinical efficacy,changes of bilirubin and treatment time before and after treatment were compared between two group of patients.RESULTS： The total effective rate of observation group were 97.8%,significantly higher than that of control group 82.6%,the difference was statistically significant（ P〈0.05）.The total bilirubin level in observation group were（75.3 ± 12.3） μmol/L,significantly lower than that in control group（ 98.8± 19.2） μmol / L,with statistically significant difference（ P〈0.05）.And the treatment time of observation group was lower than that of control group [（ 4.7 ± 1.3） d VS（ 7.8 ± 2.5） d],with statistically significant difference（ P〈0.05）.CONCLUSIONS： The clinical efficacy of medilac-vita,montmorillonite powder and yinzhihuang oral liquid in adjuvant treatment of neonatal jaundice is significant,which can effectively promote the decrease of bilirubin level.Meanwhile,this treatment regimen should be recommended for further promotion in clinical practice.

关 键 词：新生儿黄疸 茵栀黄口服液 蒙脱石散 枯草杆菌二联活菌颗粒 

分 类 号：R944.27[医药卫生—药剂学]