东南大学附属南京第二医院815例住院患者抗菌药物临床应用横断面调查  

Cross-sectional Study on Clinical Application of Antibiotics for 815 Inpatients in Nanjing the Second Affiliated Hospital of Southeast University

作　　者：张兆利[1] 熊汉申[1] 张婷婷[1] 俞斐[1] 

机构地区：[1]东南大学附属南京第二医院药学部,江苏南京210003

出　　处：《中国医院用药评价与分析》2016年第2期234-236,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解东南大学附属南京第二医院(以下简称"我院")抗菌药物横断面应用情况及合理性。方法:采用横断面调查方法调查我院某日全天的所有住院患者抗菌药物使用情况。结果:815例住院患者中,抗菌药物横断面使用率为17.00%(136/815),其中单用率为76.47%(104/136),二联使用率为19.12%(26/136),三联使用率为4.41%(6/136);用药频度排名前10位的抗菌药物种类中,3种为头孢菌素类,3种为氟喹诺酮类,2种为β-内酰胺类+酶抑制剂,1种为氨基糖苷类,1种为抗真菌药也有1种。结论:我院抗菌药物横断面使用情况总体较为合理,但是老年科、肿瘤科存在给药剂量偏大,外科围术期预防性使用抗菌药物给药时机不合理等问题,需进一步加强抗菌药物应用的管理。OBJECTIVE： To investigate the cross-section application and its rationality of antibiotics in Nanjing theSecond Affiliated Hospital of Southeast University.METHODS： Cross-sectional study was used to investigate the application of antibiotics for all the inpatients in our hospital within one day.RESULTS： Of the 815 inpatients,the cross-section application rate of antibiotics was 17.00%（136/815）,of which single-drug was 76.47%（104/136）,two-drug was 19.12%（26/136） and three-drug was 4.41%（6/136）.Among the top 10 antibiotics ranked by defined daily dose system（ DDDs）,3 were cephalosporins,3were quinolones,2 were β-Lactam ＋ enzyme inhibitors,1was aminoglycosides and 1 was antifungal drugs.CONCLUSIONS： The cross-sectional application of antibiotics in our hospital is basically rational,but the dose of antibiotics in geriatrics department and oncology department is too large and the administration time of prophylactic application of antibiotics is irrational; therefore,it is necessary to further strengthen the management in application of antibiotics.

关 键 词：抗菌药物 横断面调查 合理用药 

分 类 号：R978.1[医药卫生—药品]