D-二聚体和抗心磷脂抗体与反复自然流产的关系研究  

Relationship between D-dimer and the anticardiolinpin antibodies in patients with recurrent spontaneous aborts

作　　者：马芳芳[1] 王厚照[1] 

机构地区：[1]解放军第174医院检验科,厦门361003

出　　处：《中国优生与遗传杂志》2016年第3期77-78,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的检测反复流产患者的D-二聚体和抗心磷脂抗体,探讨D-二聚体和抗心磷脂抗体与复发性流产之间的关系。方法检测50例复发性流产患者和60例正常分娩者的D-二聚体和抗心磷脂抗体,并对两组D-二聚体水平、抗心磷脂抗体阳性率进行比较。结果复发性流产组中D-二聚体水平明显高于对照组,抗心磷脂抗体阳性率为32.00%,对照组为6.67%,两者比较有统计学意义。结论 D-二聚体和抗心磷脂抗体与血液高凝状态有相关性,患者D-二聚体和抗心磷脂抗体对复发性流产的诊断具有重要的意义。Objective：D-dimer and the anticardiolinpin antibodies were detected of all the patients,to study the relationship between D-dimer and the anticardiolinpin antibodies in patients with recurrent spontaneous aborts. Methods：To slelect and compare D-dimer,the anticardiolinpin antibodies（ACA）between 50 pations with recurrent spontaneous abortion and 60 normal deliveries. Results：There were significant differences of D-dimer between the two groups（P〈0.05）,positive tates of anticardiolinpin antibodies was 32% in patients with recurrent spontaneous aborts,was higher than that（6.67%）of control group,differences between the two groups were significant,P〈0.05. Conclusion：D-dimmer and the anticardiolinpin antibodies were correlated with high blood coagulation state in late pregnancy,The detection of D-dimmer and the anticardiolinpin antibodies is important in diagnosis of recurrent spontaneous aborts.

关 键 词：复发性流产 D-二聚体 抗心磷脂抗体 

分 类 号：R714.21[医药卫生—妇产科学]