广西地区围产儿先天性心脏病发生的影响因素分析  

Analysis of influencing factors on perinatal congenital heart disease in Guangxi

作　　者：刘湘红[1] 丘小霞[1] 刘伟[1] 曾萼[1] 韦萍[1] 姚慧[1] 李映[1] 

机构地区：[1]广西壮族自治区妇幼保健院保健部,南宁530003

出　　处：《中国优生与遗传杂志》2016年第3期88-91,共4页Chinese Journal of Birth Health & Heredity

基　　金：广西科学研究与技术开发计划项目(桂科攻1140003B-80;桂科攻1140003B-81;桂科攻1298003-4-2);广西医疗卫生重点科研课题(重2011060);广西壮族自治区卫生计生委自筹基金(Z2013259)

摘　　要：目的探讨影响广西围产儿先天性心脏病发生的相关因素。方法采用成组病例对照的研究方法,对广西7个市1398例先天性心脏病围产儿和1398例正常围产儿的父母进行问卷调查,并对可能影响先天性心脏病发生的相关因素进行单因素及多因素Logistic回归分析。结果多因素Logistic回归分析结果显示:母亲怀孕前患病用药是先天性心脏病发生的危险因素(P<0.001,OR=40.5)。结论控制或减少父母双方工作生活环境中危险因素暴露,改善父母双方健康状况,加强孕期保健和宣教对于降低胎儿先天性心脏病发生风险尤为重要。Objective：To explore the influence factors on perinatal congenital heart disease in Guangxi. Methods：By a casecontrol study group method,a questionnaire survey was conducted on parents of 1398 perinatal infant with congenital heart disease and 1398 normal perinatal infants from 7 cities in Guangxi. Univariate and multivariate logistic regression analysis was used to analyse related influencing factors. Results：The Multivariate logistic regression analysis revealed that the prevalence of medication before the mother′s pregnancy is a risk factor for congenital heart disease（P〈0.001,OR=40.5）. Conclusions：Improve the health of both parents,control or reduce the risk factors in the working environment of the parents,to strengthen the pregnancy health care and advocacy for the reduction of fetal congenital heart disease risk is particularly important.

关 键 词：先天性心脏病 影响因素 广西 问卷调查 

分 类 号：R714.5[医药卫生—妇产科学]