脊髓缺血再灌注损伤的防治概况  

The General Situation of the Prevention and Control of Spinal Cord Ischemia Reperfusion Injury

作　　者：邢晓辉[1] 李力仙[1] 郭天林[1] 梁里昂 贾玉龙[1] 刘龙[1] 

机构地区：[1]哈尔滨医科大学附属第一医院,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2016年第5期962-964,978,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81371301);黑龙江省留学归国基金项目(LC2011C16)

摘　　要：脊髓缺血-再灌注损伤(SCII)是一种严重的神经系统损伤,是缺血脊髓组织恢复血液灌注后,脊髓组织的损伤反而加重,表现为其神经损害体征和形态学改变较前更加明显,其发生机制是多因素的综合结果,治疗措施也具有多样性,脊髓缺血后脊髓微血管结构及功能的破坏和脊髓水肿等是脊髓功能损害的主要诱因,至今为止,脊髓缺血再灌注损伤的防治主要有药物及物理治疗等方法,本文作者通过查阅中外文献对脊髓缺血再灌注损伤的特征、发生机制及防治措施作一综述,希望对研究脊髓缺血再灌注损伤防治的学者能有所帮助。Spinal cord ischemic reperfusion injury（ SCII） is a serious nervous system injury, reperfusion of the spinal cord tissue after ischemia damage became more aggravate, characterized by its nerve damage before signs and morphological change is more obvious. Multifactor could contribute to the mechanism of SCII, and the prevention measures of SCII are various. The destruction of the spinal cord microvascular structure and function after spinal cord ischemia and spinal cord edema is the principal cause of spinal cord function damage, so far the spinal cord ischemia-reperfusion injury prevention and control of main methods such as drugs and physical therapy, in this paper, the author through the Chinese and foreign literatures of spinal cord ischemia-reperfusion injury make a review about the characteristics, mechanism of the injury and prevention and control them. Hope these could help the scholars to study how to prevent and control the spinal cord ischemia reperfusion injury.

关 键 词：脊柱脊髓 缺血再灌注损伤 脊髓缺血 

分 类 号：Q75[生物学—分子生物学]